21 May 2009
Is there a relationship between coronary artery calcification and serum calcium, phosphorus, pth levels and calcium-phosphorus product in renal transplant recipients ?
Z Serafïn, P Stróżecki, A Adamowicz, P Przygoński, G Dymek, Z Włodarczyk, J Manitius, W LasekAnn Transplant 2009; 14(1): 59-59 :: ID: 880414
Abstract
Background: Coronary artery calcification (CAC) is present in about 2/3 of
patients starting dialysis therapy. Serum calcium (Ca), phosphorus (P), parathormone (PTH) levels and calcium-phosphorus product (CaxP) are acknowledged factors of vascular calcifications in patients with chronic kidney disease (CKD). CAC is associated with increase of mortality in patients with
CKD. The aim of the study was to evaluate relationship between CAC and Ca, P, PTH levels and CaxP in renal transplant recipients (RTR).
Material/Methods: The study group consisted of 104 RTR (31 females and 73 males), aged 49±12 years. All patients received a graft from the deceased donors. CAC was determined with multi-detector row computed tomography as a total calcium score (CS) and calcium mass (CM). Serum Ca, P, PTH and CaxP product were analysed. Duration of renal replacement therapy was also
analysed. Glomerular fi ltration rate was calculated with abbreviated MDRD
equation (eGFR). Results are shown as mean ±SD in Table.
Results: CAC was found in 72 patients (69%). We compared RTR without CAC and those with CAC. No correlation was found between either CS and CM and: Ca, P, CaxP and PTH in the whole analysed group or in CAC+ group.
Conclusions: The prevalence of CAC in RTR is similar to that observed in patients beginning dialysis therapy. No relationship was found between serum Ca, P, PTH, CaxP product and CAC. These results may suggest that CAC occurs before beginning RTR.
Keywords: Kidney Transplantation, clinical outcome, Transplantation
In Press
08 Mar 2024 : Original article
Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persisten...Ann Transplant In Press; DOI: 10.12659/AOT.943532
14 Mar 2024 : Original article
Impact of Blood Products Transfusion on Patients in the Immediate Post-Lung Transplant Period: A Cohort StudyAnn Transplant In Press; DOI: 10.12659/AOT.943652
14 Mar 2024 : Case report
Treatment of Cavernous Transformation of Portal Vein Caused by Hepatic Cystic Echinococcosis Using Ex Vivo ...Ann Transplant In Press; DOI: 10.12659/AOT.942358
15 Mar 2024 : Review article
Approaches and Challenges in the Current Management of Cytomegalovirus in Transplant Recipients: Highlighti...Ann Transplant In Press; DOI: 10.12659/AOT.941185
Most Viewed Current Articles
05 Apr 2022 : Original article
Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver TransplantationDOI :10.12659/AOT.935604
Ann Transplant 2022; 27:e935604
12 Jan 2022 : Original article
Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...DOI :10.12659/AOT.934738
Ann Transplant 2022; 27:e934738
22 Nov 2022 : Original article
Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...DOI :10.12659/AOT.937988
Ann Transplant 2022; 27:e937988
15 Mar 2022 : Case report
Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...DOI :10.12659/AOT.935860
Ann Transplant 2022; 27:e935860