Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons

Jian Xu; Jing Feng; Yu-dong Liu; Tao Hu; Ming-jing Li; Fan Li

doi:10.12659/AOT.924093

07 July 2020: Original Paper

Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons

Jian Xu ^1BCDEF* , Jing Feng ^2BCDF* , Yu-dong Liu ^1BCD , Tao Hu ^1BCF , Ming-jing Li ^1BF , Fan Li ^1ACDEG*

DOI: 10.12659/AOT.924093

Ann Transplant 2020; 25:e924093

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Figure 1 Multiple peptide release curves of RADA16-FRM-MP and RADA16-FRM-MP-LiCl-incubated neurons from the 1st day to the 8th day. (A) Release curves for RADA16-FRM-MP-incubated neurons from the 1st day to the 8th day. (B) Release curves for RADA16-FRM-MP-LiCl-incubated neurons from the 1st day to the 8th day. * p<0.05, ** p<0.01 vs. Negative group.

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Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons

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