Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons

Jian Xu; Jing Feng; Yu-dong Liu; Tao Hu; Ming-jing Li; Fan Li

doi:10.12659/AOT.924093

07 July 2020 : Original article

Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons

Jian Xu^1BCDEF, Jing Feng^2BCDF, Yu-dong Liu^1BCD, Tao Hu^1BCF, Ming-jing Li^1BF, Fan Li^1ACDEG*

DOI: 10.12659/AOT.924093

Ann Transplant 2020; 25:e924093

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Figure 5 Measurement of neurite extension using immunofluorescence assay. (A) Measurement of neurite extension, including neurite length, amounts, and branches in SCMN neurons and DRG neurons. (B) Statistical analysis of the length of neurite in SCMN neurons and DRG neurons. (C) Statistical analysis of amount of neurite in both SCMN neurons and DRG neurons. The white arrows represent the neurite. The scale bars were added in the images. *p<0.05 vs. FRM group. # p<0.05 vs. FRM-MP group.

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Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons

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