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05 January 2021: Original Paper

Transplantation of Enterovirus 71 Virion Protein Particle Vaccine Protects Against Enterovirus 71 Infection in a Neonatal Mouse Model

Li Lei 12BCDEF , Qing Li 1BCDF , Shuhong Xu 2BCF , Mingyang Tian 2BCD , Xinghui Zheng 1BCD , Yunxia Bi 1BF , Bo Huang 1ABDEG*

DOI: 10.12659/AOT.924461

Ann Transplant 2021; 26:e924461

Figure 1 Peptide injections decrease EV71 particle levels in muscle, small intestines, and brain tissues. (A) ELISA immunogenicity analysis for the synthesized peptides (1–20). Lanes 1–20 represent the synthesized peptides. (B) cDNA bands for EV71 distribution in tissues. Lanes 1, 2, and 3 show the level of EV71 virus in skeletal muscle, small intestines, and brain tissues, respectively. (C) Quantification and statistical analysis of relative mRNA expression of the EV71 virus by a semi-quantitative RT-PCR assay. ** P<0.01 vs. the Newborn EV71 group. EV71 – enterovirus 71.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358