Transplantation of a Novel Recombinant Adeno-Associated Virus (pAAV-HE1B19K-TE1A) Demonstrates Higher Anti-Tumor Effects in Tumor Cells

Zhuo-Qing Li; Hong Shen; Kun-Xian Shu; Jian-Jun Li; Yin Tang; Jing-Jing Su; Jun Yan; Jie Yang; Ze-Qing Wang; Yan Qiu; Yong Yang; Yang Liu; Yong Zhou

doi:10.12659/AOT.925013

04 September 2020: Original Paper

Transplantation of a Novel Recombinant Adeno-Associated Virus (pAAV-HE1B19K-TE1A) Demonstrates Higher Anti-Tumor Effects in Tumor Cells

Zhuo-Qing Li ^1BCDEF* , Hong Shen ^2BCDE* , Kun-Xian Shu ^3BCDF , Jian-Jun Li ^1BCDF , Yin Tang ^4BCD , Jing-Jing Su ^4BCF , Jun Yan ^1BCD , Jie Yang ^3BCF , Ze-Qing Wang ^1BCF , Yan Qiu ^4BC , Yong Yang ^1CF , Yang Liu ^4CF , Yong Zhou ^5BDEG*

DOI: 10.12659/AOT.925013

Ann Transplant 2020; 25:e925013

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Figure 1 Synthesis of the new transgene plasmid pAAV-HE1B19K-TE1A. (A) Restriction digestion of pUC57-HE1B19K-TE1A and pAAV-IRES-ZsGreen with Mlu1 and BamH1. (B) The structure of the pAAV-HE1B19K-TE1A. (C) Positive clones were verified by restriction digestion. (D) Positive clones were verified by PCR assay.

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Transplantation of a Novel Recombinant Adeno-Associated Virus (pAAV-HE1B19K-TE1A) Demonstrates Higher Anti-Tumor Effects in Tumor Cells

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