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04 September 2020: Original Paper

Transplantation of a Novel Recombinant Adeno-Associated Virus (pAAV-HE1B19K-TE1A) Demonstrates Higher Anti-Tumor Effects in Tumor Cells

Zhuo-Qing Li 1BCDEF* , Hong Shen 2BCDE* , Kun-Xian Shu 3BCDF , Jian-Jun Li 1BCDF , Yin Tang 4BCD , Jing-Jing Su 4BCF , Jun Yan 1BCD , Jie Yang 3BCF , Ze-Qing Wang 1BCF , Yan Qiu 4BC , Yong Yang 1CF , Yang Liu 4CF , Yong Zhou 5BDEG*

DOI: 10.12659/AOT.925013

Ann Transplant 2020; 25:e925013

Figure 7 Effects of pAAV-HE1B19K-TE1A transfection on C-caspase 3 and cytochrome C expression in tumor cells and HUVEC cells using PCR assay. (A) Relative C-caspase 3 gene expression (C-caspase 3/GAPDH) and relative cytochrome C gene expression (cytochrome C/GAPDH) in HepG2 cells. (B) Relative C-caspase 3/GAPDH and relative cytochrome C/GAPDH in A549 cells. (C) Relative C-caspase 3/GAPDH and relative cytochrome C/GAPDH in BGC-803 cells. (D) Relative C-caspase 3/GAPDH and relative cytochrome C/GAPDH in HUVEC cells. * p<0.05 and *** p<0.0001 vs. pAAV-IRES-ZsGreen group in HepG2, A549, or BGC-803 cells.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358