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30 September 2022: Original Paper

Network Pharmacology-Based Exploration of the Therapeutic Mechanisms of in Renal Ischemia/Reperfusion

Jiajun Dong 1BCEF* , Mingyang Cao 2BCEF* , Hui Yu 3BCEF* , Yang Dong 24AD , Conghui Han 124AG*

DOI: 10.12659/AOT.937469

Ann Transplant 2022; 27:e937469

Figure 5 The possible regulatory mechanism of AR-mediated renal IRI. Figure created by PowerPoint for Microsoft Office 2016, Microsoft. AR – adenosine receptor; ERK – extracellular signal-regulated kinases; P38-MAPK – p38 mitogen-activated protein kinases; HIF-1α – hypoxia inducible factor 1 alpha; HIF-2α – hypoxia inducible factor 2 alpha; IL-11 – interleukin 11; S1P – sphingosine-1-phosphate; HSP27 – heat shock protein 27; AC – adenylate cyclase; PKA – protein kinase A; cAMP – adenosine 3′,5′ cyclic monophosphate; CREB – cAMP response-element binding protein; IR – ischemia/reperfusion.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358