Figure 3 A very simplified graphical interpretation of the role of the Toll-like 3 receptor of peripheral blood mononuclear cells in interaction with the interstitium of a transplanted kidney. ARG – Arginase; CD – cluster of differentiation; CXCL – chemokine (C-X-C motif) ligand; EGF – Epidermal growth factor; FCF – favorable course of follow-up; IFNB – interferon beta; IL – Interleukin; IL1D – interleukin 1 soluble domain; IRF – Interferon regulatory factor; MHC – major histocompatibility complex; MMPs – Matrix metalloproteinases; NOX – NADPH oxidase; O- – oxygen radical; O2 – oxygen; TCR – T-cell receptor; TGFB – Transforming growth factor beta; TH – helper lymphocyte; TLR3- Toll-like receptor 3; TNF – Tumor necrosis factor; VEGF – vascular endothelial growth factor. The figure was prepared using Adobe Photoshop and Microsoft Paint.