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11 November 2025 : Original article  

Invasive Coronary Physiology Assessment for Detecting Microcirculatory Dysfunction in Heart Transplant Recipients

Mateusz Sokolski ORCID logo ABCDEFG 1,2*, Natalia Oliwia Bernacka ORCID logo CDEF 3, Wiktoria Zychla CDEF 3, Magdalena J. Cielecka ORCID logo BE 1,2, Mateusz Rakowski ORCID logo BE 2,4, Maciej Bochenek ORCID logo BE 1,2, Wiktor Kuliczkowski ORCID logo BE 2,5, Roman Przybylski ORCID logo BEG 2,6, Michał Zakliczyński ORCID logo ABEG 1,2

DOI: 10.12659/AOT.950138

Ann Transplant 2025; 30:e950138

Figure 2 (A) Comparison of body mass index (BMI). The box plot compares the distribution of BMI (kg/m2) among the 2 groups of patients: heart transplant recipients with normal coronary microcirculation and those with coronary microvascular dysfunction (CMD). The boxes extend from the lower quartile (Q1) to the upper quartile (Q3), indicating the interquartile range (IQR). In both groups, the median BMI is represented by the horizontal line inside the box. The whiskers extend to the minimum and maximum values within 1.5×IQR of the quartiles. There were no outliners. The figure was created in Python 3.11.13 with matplotlib 3.10.0, pandas 2.2.2. (B) Comparison of time since transplantation. The box plot compares the distribution of time since transplantation (years) among the 2 groups of patients: heart transplant recipients with normal coronary microcirculation and those with CMD. The boxes extend from the lower quartile (Q1) to the upper quartile (Q3), indicating the interquartile range (IQR). In both groups, the median time since transplantation is represented by the horizontal line inside the box. The whiskers extend to minimum and maximum values within 1.5×IQR quartiles. In the group with normal coronary microcirculation, there were outliners, shown as white dots. The figure was created in Python 3.11.13 with matplotlib 3.10.0, pandas 2.2.2. (C) Comparison of pacemaker implantation. The bar chart compares the number of patients who required pacemaker implantation after heart transplantation among the 2 groups: heart transplant recipients with normal coronary microcirculation and those with CMD. The figure was created in Python 3.11.13 with matplotlib 3.10.0, pandas 2.2.2, numpy 2.0.2. (D) Comparison of triglyceride levels. The box plot compares the distribution of triglyceride levels (mg/dL) among the 2 groups of patients: heart transplant recipients with normal coronary microcirculation and those with CMD. The boxes extend from the lower quartile (Q1) to the upper quartile (Q3), indicating the interquartile range (IQR). In both groups, the median triglyceride level is represented by the horizontal line inside the box. The whiskers extend to the minimum and maximum values within 1.5×IQR of the quartiles. There were no outliners. The figure was created in Python 3.11.13 with matplotlib 3.10.0, pandas 2.2.2.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358