Identification and Validation of Liver Transplantation-Induced Acute Lung Injury Biomarkers Using a Bioinformatics and Experimental Approach

Yang Guiting; Shengfeng Zhang; Liu Ji; Chengmei Lv; Chen Zhao; Maoyao Ling; Xiaoting Liao; Linghui Pan

doi:10.12659/AOT.950289

17 February 2026 : Database Analysis

Identification and Validation of Liver Transplantation-Induced Acute Lung Injury Biomarkers Using a Bioinformatics and Experimental Approach

Yang Guiting

^{ABCDEFG 1,2,3,4,5}, Shengfeng Zhang^{ABCDEFG 2}, Liu Ji^{ABCDE 1,3,4,5}, Chengmei Lv^{BCD 6,2,3,4,5}, Chen Zhao^{BCD 2}, Maoyao Ling^{CD 1,3,4,5}, Xiaoting Liao^{CDE 1,3,4,5}, Linghui Pan^{ACDEFG 1,3,4,5*}

DOI: 10.12659/AOT.950289

Ann Transplant 2026; 31:e950289

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Figure 4 Validation of the efficacy of the hub genes diagnostic. (A) Nomogram of the hub genes. (B) The Decision Curve Analysis (DCA) of the nomogram. (C) Calibration curve of the nomogram. (D–F) The Receiver Operating Characteristic (ROC) curve of the hub genes: CXCL3, CD48 and IRAK3.

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Identification and Validation of Liver Transplantation-Induced Acute Lung Injury Biomarkers Using a Bioinformatics and Experimental Approach

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