09 June 2026 : Original article
Brain Death–Induced Systolic Ventricular Dysfunction and Its Association With NLRP3-Related Inflammatory Signaling in a Murine Model
Lei Huang ABCDEFG 1,2, Kevin P. Zbierski B 3, Ye Yuan CD 2, Siyuan Dong CD 2, Jacob Razzouk C 3, David G. Rabkin
ABCDEFG 3*
DOI: 10.12659/AOT.951930
Ann Transplant 2026; 31:e951930
Figure 5 Phase II levels of P2X7 and PPAR-gamma in left ventricle at 60 minutes after brain death (BD). (A) Representative western blot bands from 2 independent animal sets (loading control β-actin band for PPAR-γ is the same as that used for NLRP3 and IL-1β in Figure 4A, as these proteins were probed on the same membrane). (B, C) Quantitative analysis of P2X7 and PPAR-gamma expressions. n=6/group.