Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

24 May 2019 : Original article  

Comparison of Ipsilateral and Contralateral Simultaneous Pancreas and Kidney Transplantation: A Single-Center Analysis with 5-Year Outcome

Stavros Papachristos1ACDEF*, Afshin Tavakoli1ABD, Raman Dhanda1B, Ravi Pararajasingam1AB, Tunde Campbell1BDE, Bence Forgacs1ABCDE

DOI: 10.12659/AOT.912633

Ann Transplant 2019; 24:298-303

Abstract

BACKGROUND: It is routine to implant the pancreas on the right and the renal graft on the left iliac fossa during a simultaneous kidney and pancreas transplant (cSPK). Ipsilateral placement of both organs on the same side raises concerns that the pancreas graft might compromise the distally placed kidney. However, ipsilateral SPK (iSPK) can be faster than the conventional contralateral graft placement and allows for preservation of the other side for future transplants.

MATERIAL AND METHODS: In a single unit, 67 SPK transplantations (cSPK n=49, iSPK n=18) were performed from 2008 to 2011. The decision for graft placement was made during the procedure. Donor and recipient demographics, surgical complications, reoperations, surgical time, and patient and graft survival with 5-year follow-up were compared between the 2 groups.

RESULTS: Duration of operation was shorter in the iSPK group. Recipient and donor demographics were comparable, apart from more females receiving ipsilateral graft placement. The broader female pelvis was probably the determining factor contributing to this outcome. The iSPK group included marginally younger recipients. The ipsilateral group also demonstrated a trend to improved survival of patient, pancreas, and kidney graft, at 1- and 5-year follow-up. There was no difference in complication rates between the 2 groups.

CONCLUSIONS: There were no significant differences in overall outcomes. iSPK is a safe procedure, which proves similar patient and graft survival as with cSPK. Both procedures have comparable surgical complication rates. iSPK is a safe and quicker procedure that allows for preservation of the contralateral side for potential subsequent transplants.

Keywords: Kidney Transplantation, Organ Transplantation, Pancreas Transplantation, Age Factors, Follow-Up Studies, Graft Survival, operative time, Postoperative Complications, Sex Factors

Add Comment 0 Comments

In Press

Original article  

Urinary Chemokines CXCL9 and CXCL10 Are Non-Invasive Biomarkers of Kidney Transplant Rejection

Ann Transplant In Press; DOI: 10.12659/AOT.944762  

Original article  

Risk Factors for Graft Failure After Penetrating Keratoplasty in Eastern China from 2018 to 2021

Ann Transplant In Press; DOI: 10.12659/AOT.945388  

Original article  

Predictive Model for Post-Transplant Renal Fibrosis Using Ultrasound Shear Wave Elastography

Ann Transplant In Press; DOI: 10.12659/AOT.945699  

Original article  

The Long-Acting Glucagon-Like Peptide-2 Analog Apraglutide Enhances Intestinal Protection and Survival Afte...

Ann Transplant In Press; DOI: 10.12659/AOT.945249  

Most Viewed Current Articles

05 Apr 2022 : Original article   12,977

Impact of Statins on Hepatocellular Carcinoma Recurrence After Living-Donor Liver Transplantation

DOI :10.12659/AOT.935604

Ann Transplant 2022; 27:e935604

22 Nov 2022 : Original article   10,134

Long-Term Effects of Everolimus-Facilitated Tacrolimus Reduction in Living-Donor Liver Transplant Recipient...

DOI :10.12659/AOT.937988

Ann Transplant 2022; 27:e937988

12 Jan 2022 : Original article   9,446

Risk Factors for Developing BK Virus-Associated Nephropathy: A Single-Center Retrospective Cohort Study of ...

DOI :10.12659/AOT.934738

Ann Transplant 2022; 27:e934738

15 Mar 2022 : Case report   7,198

Combined Liver, Pancreas-Duodenum, and Kidney Transplantation for Patients with Hepatitis B Cirrhosis, Urem...

DOI :10.12659/AOT.935860

Ann Transplant 2022; 27:e935860

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358