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23 June 2020: Original Paper

Dynamic Metabolomics Study of the Bile Acid Pathway During Perioperative Primary Hepatic Carcinoma Following Liver Transplantation

Weiguo Sui 1A* , Qing Gan 1CE* , Fuhua Liu 1B , Minglin Ou 1D , Bingguo Wang 1F , Songbai Liao 1F , Liusheng Lai 1F , Huaizhou Chen 1D , Ming Yang 1G* , Yong Dai 2AG*

DOI: 10.12659/AOT.921844

Ann Transplant 2020; 25:e921844

Table 3 The differential comparison for ionic strength of metabolites.

GroupsTaurocholic acidTaurochenodeoxycholic acidChenodeoxycholic acid glycine conjugateGlycocholic acid
VIPFold changeq-valueVIPfold changeq-valueVIPfold changeq-valueVIPfold changeq-value
Pre NC3.7255* 121.63* 0.0250* 2.9581* 33.078* 0.0442* 2.5999* 6.2715* 0.0106* 2.9258* 9.1140* 0.0151*
P1 Pre0.19950.87060.583670.95350.63650.31681.49280.64840.10040.90491.18970.3272
P3 P11.05532.17770.57270.36411.80090.70850.52881.14750.66671.71251.84600.3533
P7 P30.62840.34810.99970.10900.327010.99970.77021.18030.99970.00391.34900.9999
P7 NC3.7079* 80.275* 0.0243* 1.926712.3990.19301.24585.50760.28662.9072* 27.001* 0.0384*
* VIP from the OPLS-DA greater than 1.0, q-value

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358