13 October 2020 : Original article
Pediatric Liver Transplantation for Alagille Syndrome: Anesthetic Evaluation and Perioperative Management
Wen-He Yang1ABF, Liang Zhang1ABCDEF*, Fu-Shan Xue1ADG, Azmat Riaz2EF, Zhi-Jun Zhu345ADGDOI: 10.12659/AOT.924282
Ann Transplant 2020; 25:e924282
Table 4 Postoperative surgical complications and re-operations in pediatric AGS and BA recipients.
Variables | AGS (n=11) | BA (n=98) | P-value |
---|---|---|---|
Age (mo) | 23.5 (12.0–73.0) | 30.9 (10.3–73.3) | 0.007 |
Male gender (%) | 8 (72.7) | 54 (55.1) | 0.345 |
Height (cm) | 82.0 (71.5–102.0) | 70.0 (65.4–90.3) | 0.038 |
Weight (kg) | 8.5 (7.5–15) | 8.5 (7.0–13.3) | 0.466 |
Z Score* | −2.69 (−3.49 – −1.31) | −1.18 (−2.30 – −0.13) | 0.015 |
PELD score | 9 (3–15) | 10 (−3–21) | 0.759 |
Preoperative history of abdominal operation (%) | 9 (81.8) | 90 (91.8%) | 0.265 |
Living-related donor (%) | 8 (72.7) | 75 (76.5) | 0.722 |
Partial graft (%) | 10 (90.9) | 78 (79.6) | 0.687 |
Graft weight (g) | 267 (226–317) | 259 (210–326) | 0.644 |
GRWR (%) | 2.68±0.91 | 2.92±0.96 | 0.432 |
Surgical complications | 6 (54.5) | 22 (22.4) | 0.031 |
Re-operations (%) | 5 (45.5) | 15 (15.3) | 0.028 |
* Height for age Z score (Data form Chinese Center for Disease Control and Prevention). AGS – Alagille syndrome; BA – biliary atresia; GRWR – graft-to-recipient weight ratio; LT – liver transplantation; PELD – Pediatric End-stage Liver Disease. |