13 November 2020 : Original article
Single-Center Retrospective Analysis of Prophylaxis and Treatment of Pneumocystis carinii Pneumonia in Patients with Renal Dysfunction After Renal Transplantation
Jianyong Pan1C, Yingxin Fu1A*, Yu Cao1C, Gang Feng1F, Jie Zhao1D, Xiaofeng Shi1D, Chunbai Mo1A, Wenli Song1F, Zhongyang Shen1AGDOI: 10.12659/AOT.925126
Ann Transplant 2020; 25:e925126
Table 2 Comparison of immunosuppressive agents and early postoperative complications among 2 groups.
| ARF (n=37) | NRF (n=31) | P value | |
|---|---|---|---|
| Induction therapy | 0.552 | ||
| Polyclonal antibodies | 6 (16.2%) | 3 (9.7%) | |
| Anti-CD25 mAbs | 27 (73%) | 26 (83.9%) | |
| Only steroids | 4 (10.8%) | 2 (6.5%) | |
| CNI | 0.792 | ||
| Tac | 29 (78.4%) | 26 (83.9%) | |
| CsA | 8 (21.6%) | 5 (16.1%) | |
| CNI concentration | 0.566 | ||
| High | 17 (45.9%) | 20 (64.5%) | |
| Low | 20 (54.1%) | 11 (35.5%) | |
| MPA dosage | 0.611 | ||
| High | 18 (48.6%) | 17 (54.8%) | |
| Low | 19 (51.4%) | 14 (45.2%) | |
| Perioperative infection | 5 (13.5%) | 3 (9.7%) | >0.05 |
| DGF | 2 (5.4%) | 1 (3.2%) | 0.665 |
| AR | 10 (27%) | 1 (3.2%) | 0.008 |
| IS – immunosuppressive regimen; CsA – cyclosporin A; MMF – mycophenolate mofetil; MPA – mycophenolic acid; CNI high dose – tacrolimus ≥7 ng/mL, CsA ≥150 ng/mL; CNI low dose – tacrolimus | |||