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13 November 2020 : Original article  

Single-Center Retrospective Analysis of Prophylaxis and Treatment of Pneumocystis carinii Pneumonia in Patients with Renal Dysfunction After Renal Transplantation

Jianyong Pan1C, Yingxin Fu1A*, Yu Cao1C, Gang Feng1F, Jie Zhao1D, Xiaofeng Shi1D, Chunbai Mo1A, Wenli Song1F, Zhongyang Shen1AG

DOI: 10.12659/AOT.925126

Ann Transplant 2020; 25:e925126

Table 3 Comparison of the onset and treatment characteristics of PCP among 2 groups.

ARF (n = 37)NRF (n = 31)P value
Onset (months)5.9 (4–8.7)5.4 (2.7–10.4)0.218
TMP-SMX prophylaxis15 (40.5%)2 (6.5%)0.047
PCP symptom
 Fever30 (81.1%)27 (87.1%)0.734
 Cough14 (37.8%)9 (29%)0.445
 Suffocation18 (48.6%)10 (32.3%)0.171
 Weakness3 (8.1%)00.304
 Diarrhea1 (2.7%)0>0.05
CMV(+)16 (43.2%)12 (38.7%)0.705
Neutrophil granulocyte(10/L)6.5 (4.8–8.5)6.9 (5.4–8.5)0.487
Lymphocyte count(10/L)0.6 (0.5–0.9)1.1 (0.7–1.6)
BG detection(+)18 (48.6%)8 (25.8%)0.054
PMD20 (54.1%)16 (51.6%)0.841
Anti-PCP Steroid usage21 (56.8%)16 (51.6%)0.671
Anti PCP TMP-SMX dose(g)6 (4.3–6)6 (3–6)0.482
Caspofungin25 (67.6%)18 (58.1%)0.418
BG detection – serum 1-3-(Beta-D) Glucan concentration; PMD – pathogenic microbiological diagnosis; ARF – abnormal renal function group; NRF – normal renal function.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358