24 November 2020 : Original article
Role of Renal Replacement Therapy During the Peri-Transplant Period of Heart Transplantation
Sua Lee1ABCDEF, Tae Hyun Ban2ABCDEF*, Hoon Suk Park2BF, Suk Min Seo3EF, Byung Ha Chung45CF, Jihyang Lim6EF, Eun-Jee Oh7BC, Bumsoon Choi2EF, Cheol Whee Park4EF, Chul Woo Yang45CDE, Sang Hong Baek8DE, Yong-Soo Kim4EFDOI: 10.12659/AOT.925648
Ann Transplant 2020; 25:e925648
Table 2 Comparison of clinical outcomes between non-RRT and RRT groups.
| Variable | Non-RRT (n=5) | RRT (n=10) | P value |
|---|---|---|---|
| Time of AKI, n (%) | 1.000 | ||
| Pre-transplantation | 4 (80.0) | 9 (90.0) | |
| Post-transplantation | 1 (20.0) | 1 (10.0) | |
| AKI stage, n (%) | 0.661 | ||
| Stage I | 2 (40.0) | 2 (20.0) | |
| Stage II | 1 (20.0) | 4 (40.0) | |
| Stage III | 2 (40.0) | 4 (40.0) | |
| ECMO during pre-transplant period, n (%) | 4 (80.0) | 9 (90.0) | 1.000 |
| Duration of ECMO (days), mean±SD | 11.3±12.7 | 10.2±6.8 | 0.796 |
| Urine volume during AKI period, ml/kg/hr, mean±SD | 1.6±1.2 | 1.4±1.2 | 0.660 |
| Interval from AKI to RRT start (days), mean±SD | NA | 1.3±1.3 | |
| Duration of RRT (days), median (IQR) | NA | 19.0 (5.0, 27.0) | |
| Type of RRT, n (%) | |||
| CRRT | NA | 9 (90.0) | |
| Intermittent HD | NA | 1 (10.0) | |
| Recovery from AKI, n (%) | 5 (100) | 7 (70.0) | 0.505 |
| Full recovery | 4 (80.0) | 4 (40.0) | 0.576 |
| Partial recovery | 1 (20.0) | 3 (30.0) | 0.576 |
| Interval from AKI to renal function recovery after HT (days), median (IQR) | 6.0 (3.5, 15.5) | 22.0 (20.0, 64.0) | 0.088 |
| AKI – acute kidney injury; CRRT – continuous renal replacement therapy; ECMO – extracorporeal membrane oxygenation; HD – hemodialysis; HT – heart transplantation; IQR – interquartile range; RRT – renal replacement therapy; SD – standard deviation. | |||