Logo Annals of Transplantation Logo Annals of Transplantation Logo Annals of Transplantation

24 July 2020: Review Paper

Kidney Transplantation in the Times of COVID-19 – A Literature Review

Ashraf Imam ACDEF** , Sadi A. Abukhalaf ABCEF* , Riham Imam BCD , Samir Abu-Gazala AEF , Hadar Merhav ACD** , Abed Khalaileh ABCEF**

DOI: 10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

Table 4 Management and Outcomes of the 58 Reported Kidney Transplant Patients Who Encountered COVID-19.

Baseline Immunosuppression
 Tacrolimus48/58 (82.7%)
 Mycophenolate mofetil46/58 (79.3%)
 Prednisone47/58 (81%)
 Azathioprine2/58 (3.4%)
 Everolimus3/58 (5.2%)
 Ciclosporin4/58 (6.8%)
 Sirolimus2/58 (3.4%)
 Mizoribine1/58 (1.7%)
 Held tacrolimus23/48 (47.9%)
 Reduced tacrolimus10/48 (20.8%)
 No change tacrolimus15/48 (25.8%)
 Held mycophenolate mofetil37/46 (80.4%)
 Reduced mycophenolate mofetil2/46 (4.3%)
 No change mycophenolate mofetil7/46 (15.2%)
 Held prednisone7/47 (14.8%)
 Increased prednisone2/47 (4.2%)
 No change prednisone38/47 (80.8%)
 AzathioprineHeld 1; No change 1
 EverolimusHeld 2; No change 1
 CiclosporinHeld 2; No change 2
 SirolimusHeld 1; No change 1
 MizoribineHeld 1
Other Tx
 Lopinavir/Ritonavir12/58 (20.6%)
 Hydroxychloroquine25/58 (43.1%)
 Azithromycin9/58 (15.5%)
 Oseltamivir8/58 (13.8%)
 Antibiotics24/58 (41.3%)
 Intravenous methylprednisolone19/58 (32.7%)
 Intravenous immunoglobulin15/58 (25.8%)
 Unspecified antivirals10/58 (17.2%)
 Interferon α, β3/58 (5.2%)
 Tocilizumab2/58 (3.4%)
 Remdesivir1/58 (1.7%)
ICU admission11/58 (19%)
MV requirement13/58 (22.4%)
Clinically recovered/Discharged36/58 (62%)
 Illness days duration (median, Range)17.5 (7–48)
 Alive but suffers/In hospital13/58 (22.4%)
 Illness days duration (median, range)14 (7–49)
Death9/58 (15.5%)
 Illness days duration (median, range)9 (5–40)

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358