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24 July 2020: Review Paper

Kidney Transplantation in the Times of COVID-19 – A Literature Review

Ashraf Imam ACDEF** , Sadi A. Abukhalaf ABCEF* , Riham Imam BCD , Samir Abu-Gazala AEF , Hadar Merhav ACD** , Abed Khalaileh ABCEF**

DOI: 10.12659/AOT.925755

Ann Transplant 2020; 25:e925755

Table 5 Characteristics and management of the COVID-19 kidney transplant patients with death as the outcome.

Variable (n=9)Value
Age in years (mean)66.2
Sex, Male55.5%
Kidney transplant years age (Mean)9.7
 Lymphopenia (66.6%
 High CRP (>5 mg/dl)66.6%
 Acute kidney injury44.4%
Baseline Immunosuppression regimen
 Tac, MMF, Pred44.4%
 Held tacrolimus3/6 (50%)
 Reduced tacrolimus2/6 (33.3%)
 No change tacrolimus1/6 (16.6%)
 Held mycophenolate mofetil6/6 (100%)
 Held prednisone2/7 (28.5%)
 No change prednisone5/7 (71.4%)
 Held ciclosporin1/1 (100%)
 Held sirolimus1/1 (100%)
 Held mizoribine1/1 (100%)
Tx targets COVID-19
 Intravenous methylprednisolone33.3%
 Intravenous immunoglobulin22.2%
ICU admission33.3%
MV requirement55.5%
Disease days duration (median, range)9 (5–40)

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358