19 February 2021 : Original article
Short- and Long-Term Outcomes of Different Reperfusion Sequences in Liver Transplantation
Ann-Kathrin Eichelmann1BCEF*, Thomas Vogel1ABE, Ann-Kathrin Fuchs1BC, Philipp Houben1DE, Shadi Katou1BDF, Felix Becker1CD, Hartmut H. Schmidt2AD, Christian Wilms2DF, Andreas Pascher1BD, Jens G. Brockmann1ACDEDOI: 10.12659/AOT.926847
Ann Transplant 2021; 26:e926847
Table 3 Operative and (early) postoperative data.
| PV | A | SIM | p | ||
|---|---|---|---|---|---|
| Operative data | Cold ischemia (min) | 485±157 | 526±141 | 554±105 | 0.32 |
| Warm ischemia (min) | 36±10 | 29±6 | 48±6 | 0.001 | |
| T-Drain (yes) | 9 (36%) | 3 (14%) | 1 (7%) | 0.06 | |
| Portocaval shunt | 0 | 22 (100%) | 8 (57%) | 0.001 | |
| Operating time (min) | 335±81 | 339±81 | 331±109 | 0.73 | |
| RBC (units) | 10 (0–50) | 7 (1–35) | 7 (3–44) | 0.62 | |
| FFP (units) | 24 (4–67) | 19 (4–52) | 21 (7–61) | 0.61 | |
| Platelets (units) | 2.2 (0–6) | 2 (0–7) | 3.1 (0–13) | 0.76 | |
| Postoperative data | Overall hospital stay (median, d) | 30 (9–132) | 30 (14–93) | 28 (16–111) | 0.99 |
| Intensive Care Unit | 25 (9–129) | 26 (13–83) | 28 (16–106) | 0.74 | |
| Intermediate Care | 15 (0–76) | 19 (0–45) | 17 (3–80) | 0.32 | |
| 30d mortality | 4 (16%) | 0 | 1 (7%) | 0.13 | |
| 60d mortality | 7 (28%) | 0 | 2 (14%) | 0.03 | |
| Complications within 60d | |||||
| Bleeding | 5 (20%) | 4 (18%) | 3 (21%) | 0.9 | |
| Biliary | 2 (8%) | 1 (5%) | 1 (7%) | 0.9 | |
| Vascular | 1 (4%) | 1 (5%) | 0 | 0.73 | |
| Other | 2 (8%) | 3 (14%) | 1 (7%) | 0.75 | |
| Acute rejection | 1 (4%) | 4 (18%) | 0 | 0.09 | |
| Re-Transplantation within 30d | 5 (20%) | 2 (9%) | 0 | 0.15 | |
| Labaratory data (peak level) | |||||
| AST (U/l) | 4773±4794 | 1249±819 | 2086±1412 | 0.01 | |
| ALT (U/l) | 2850±3424 | 819±661 | 1461±1287 | 0.03 | |
| Bilirubin (mg/dl) | 10.7±9 | 8.6±11 | 6.8±5 | 0.57 | |
| gGT (U/l) | 415±329 | 554±408 | 1736±2622 | 0.2 | |
| PV – primary portal venous reperfusion; A – primary arterial reperfusion; SIM – simultaneous reperfusion; Min – minute; RBC – red blood cell packets; FFP – fresh frozen plasma; d – days; AST – aspartate aminotransferase; ALT – alanine aminotransferase. | |||||