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19 February 2021: Original Paper

Short- and Long-Term Outcomes of Different Reperfusion Sequences in Liver Transplantation

Ann-Kathrin Eichelmann 1BCEF** , Thomas Vogel 1ABE* , Ann-Kathrin Fuchs 1BC , Philipp Houben 1DE , Shadi Katou 1BDF , Felix Becker 1CD , Hartmut H. Schmidt 2AD , Christian Wilms 2DF , Andreas Pascher 1BD , Jens G. Brockmann 1ACDE

DOI: 10.12659/AOT.926847

Ann Transplant 2021; 26:e926847

Table 4 12-year post-liver transplant morbidity and mortality.

PVASIMTotalp
Alive after 12 years7 (31.8%)7 (28%)7 (50%)21 (35%)0.36
Overall survival (median, d)848 (0–4982)1383 (68–4507)3432 (1–4883)1733 (0–4982)0.16
 Mean (d)1745±20222142±17322955±17322166±1886
 Years4.85.98.15.9
Retransplantation7 (31.8%)3 (13.6%)010 (16.4%)0.073
 >1 retransplantation2 (2OLT)00
Graft survival (median, d)180 (0–4623)1259 (2–4507)3432 (1–4883)1186 (0–4883)0.003
 Mean (d)1191±17222015±17712955±17321893±1846
 Years3.35.58.15.2
Development of biliary stricture (yes)7 (28%)5 (22.7%)3 (21.4%)15 (24.6%)0.27
ERCP necessity (yes)11 (42.6%)9 (40.9%)6 (42.9%)26 (42.6%)0.9
Number of ERCP8.6 (1–40)2.3 (1–8)5.5 (1–25)5.60.31
Rejection treatment (n=49)N=196 (31.6%)N=181 (5.3%)N=121 (8.3%)N=498 (16.3%)0.07
Laboratory data
 3 year
  AST53±44109±21325±774±1520.28
  ALT43±3263±7520±1047±560.11
  Bilirubin1±1.42.5±6.90.5±0.31.3±4.50.4
 10 year
  AST33±722±548±6134±370.04
  ALT29±827±1241±4632±290.7
 Bilirubin0.8±0.80.4±0.20.4±0.20.5±0.460.6
PV – primary portal venous reperfusion; A – primary arterial reperfusion; SIM – simultaneous reperfusion; d – days; ERCP – endoscopic retrograde cholangiopancreatography; AST – aspartate aminotransferase; ALT – alanine aminotransferase.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358