15 December 2020 : Original article
The Impact of Hypothermic Pulsatile Machine Perfusion Versus Static Cold Storage: A Donor-Matched Paired Analysis in a Scenario of High Incidence of Delayed Kidney Graft Function
Tainá Veras de Sandes-Freitas12ABCDEF*, Silvana Daher Costa12ABDEF, Luis Gustavo Modelli de Andrade3CDEF, Celi Melo Girão2BCEF, Paula Frassinetti Castelo Branco Camurça Fernandes4DEF, Claudia Maria Costa de Oliveira25DEF, Ronaldo de Matos Esmeraldo2ADEFDOI: 10.12659/AOT.927010
Ann Transplant 2020; 25:e927010
Table 2 Recipient demographic and clinical characteristics.
| SC groupN=103 | MP groupN=103 | P value | |
|---|---|---|---|
| n(%) | 59 (57.3) | 58 (56.3) | 1.000 |
| mean±SD | 45.9±15.0 | 39.9±18.2 | 0.011 |
| mean±SD | 24.5±4.7 | 22.6±4.7 | 0.004 |
| n (%) | 0.857 | ||
| Caucasian | 9 (8.7) | 11 (10.7) | |
| Mixed/Hispanic | 89 (86.4) | 86 (83.5) | |
| Afro-Brazilian | 5 (4.9) | 6 (5.8) | |
| n (%) | 0.059 | ||
| Unknown | 29 (28.3) | 41 (39.8) | |
| Hypertension | 28 (27.2) | 27 (26.2) | |
| Diabetes | 18 (17.5) | 9 (8.7) | |
| Glomerulonephritis | 8 (7.8) | 6 (5.8) | |
| Urological | 16 (15.5) | 8 (7.8) | |
| PKD | 3 (2.9) | 10 (9.7) | |
| Other | 1 (1.0) | 2 (1.9) | |
| n (%) | 19 (18.4) | 10 (9.7) | 0.108 |
| median (IQR) | 35 (20–58) | 36 (18–60) | 0.937 |
| n (%) | 9 (8.7) | 12 (11.7) | 0.646 |
| median (IQR) | 0 (0–1.9) | 0 (0–17) | 0.360 |
| median (IQR) | 0 (0–0) | 0 (0–0) | 0.804 |
| n(%) | 3 (2.9) | 16 (15.5) | 0.003 |
| median (IQR) | 3 (3–4) | 3 (3–4) | 0.299 |
| mean±SD | 20.8±4.1 | 28.1±6.3 | <0.001 |
| mean±SD | 20.8±4.1 | 15.8±6.2 | <0.001 |
| mean±SD | n.a | 12.3±5.7 | n.a |
| mean±SD | 36.0±12.3 | 36.6±9.5 | 0.690 |
| n(%) | 101 (98.1) | 102 (99.0) | 1.000 |
| SC – static cold; MP – machine perfusion; BMI – body mass index; ESRD – end-stage renal disease; KT – kidney transplant; PKD – polycystic kidney disease; PRA – panel reactive antibodies; DSA – donor specific antibodies; HLA – human leukocyte antigen; CIT – cold ischemia time; VAT – vascular anastomosis time; rATG – rabbit antithymocyte globulin; na – not applicable; IQR – interquartile range; SD – standard deviation. | |||