09 February 2021 : Original article
Association Between Trough Level of Tacrolimus and Change in Estimated Glomerular Filtration Rate 1 Year After Living Donor Liver Transplantation
Kumiko Muta1ABCDEF*, Mineaki Kitamura1ABCDE, Masaaki Hidaka2BE, Yuki Ota1AB, Takanobu Hara2BE, Akihiko Soyama2BD, Satoshi Miuma3BE, Hisamitsu Miyaaki3BE, Kazuhiko Nakao3BE, Susumu Eguchi2BDE, Hiroshi Mukae4DE, Tomoya Nishino1ADEDOI: 10.12659/AOT.928858
Ann Transplant 2021; 26:e928858
Table 4 Multivariate logistic regression analysis for elevated eGFR 1 year after living donor liver transplantation.
<Model 1> | Odds ratio | 95% CI | p Value |
---|---|---|---|
Pretransplant diuretics | 0.60 | 0.18–2.02 | 0.41 |
Pretransplant hemoglobin | 0.98 | 0.77–1.26 | 0.90 |
Pretransplant albumin | 0.82 | 0.36–1.88 | 0.64 |
Pretransplant eGFR | 0.92 | 0.89–0.95 | |
Trough value of TAC 1 year after LDLT | 0.97 | 0.79–1.18 | 0.76 |
Posttransplant use of TAC+Mycophenolate mofetil | 1.36 | 0.47–3.94 | 0.57 |
Pretransplant diuretics | 2.52 | 1.02–6.22 | 0.04 |
Pretransplant hemoglobin | 0.88 | 0.72–1.00 | 0.20 |
Pretransplant albumin | 1.13 | 0.58–2.21 | 0.72 |
Trough value of TAC 1 year after LDLT | 0.85 | 0.72–0.99 | 0.04 |
Posttransplant use of TAC+Mycophenolate mofetil | 1.67 | 0.73–3.80 | 0.22 |
95% CI – 95% confidence interval; eGFR – estimated glomerular filtration rate; LDLT – living donor liver transplantation; TAC – tacrolimus. |