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09 February 2021 : Original article  

Association Between Trough Level of Tacrolimus and Change in Estimated Glomerular Filtration Rate 1 Year After Living Donor Liver Transplantation

Kumiko Muta1ABCDEF*, Mineaki Kitamura1ABCDE, Masaaki Hidaka2BE, Yuki Ota1AB, Takanobu Hara2BE, Akihiko Soyama2BD, Satoshi Miuma3BE, Hisamitsu Miyaaki3BE, Kazuhiko Nakao3BE, Susumu Eguchi2BDE, Hiroshi Mukae4DE, Tomoya Nishino1ADE

DOI: 10.12659/AOT.928858

Ann Transplant 2021; 26:e928858

Table 4 Multivariate logistic regression analysis for elevated eGFR 1 year after living donor liver transplantation.

<Model 1>Odds ratio95% CIp Value
Pretransplant diuretics0.600.18–2.020.41
Pretransplant hemoglobin0.980.77–1.260.90
Pretransplant albumin0.820.36–1.880.64
Pretransplant eGFR0.920.89–0.95
Trough value of TAC 1 year after LDLT0.970.79–1.180.76
Posttransplant use of TAC+Mycophenolate mofetil1.360.47–3.940.57
Pretransplant diuretics2.521.02–6.220.04
Pretransplant hemoglobin0.880.72–1.000.20
Pretransplant albumin1.130.58–2.210.72
Trough value of TAC 1 year after LDLT0.850.72–0.990.04
Posttransplant use of TAC+Mycophenolate mofetil1.670.73–3.800.22
95% CI – 95% confidence interval; eGFR – estimated glomerular filtration rate; LDLT – living donor liver transplantation; TAC – tacrolimus.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358