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18 May 2021: Original Paper

Diagnostic Dilemma and Treatment Outcome in Acute Liver Failure Due to Wilson’s Disease

Rafał Stankiewicz ABCDEF* , Waldemar Patkowski DG , Krzysztof Zieniewicz ADG

DOI: 10.12659/AOT.930146

Ann Transplant 2021; 26:e930146

Table 1 Clinical and laboratory data of the study cohort.

Age (mean, range)24.9 (18–45)
Sex (F/M)17/3
Ascites18 (90.0%)
Grade of encephalopathy
I/II5 (25.0%)
III/IV15 (75.0%)
Hypoglycemia2 (10.0%)
Total bilirubin (mg/dL)35.31±14.256.4–53.4
WBC (10/L)14.57±10.422.11–44.63
AST (IU/L)240±21094–1032
ALT (IU/L)134±30011–1385
ALP (mg/dL)100±10512–479
Prothrombin index (%)31.45±10.5710–50
Prothrombin time (s.)45.42±23.4125.1–120
Albumin (mg/dL)2.73±0.582.2–4.3
Urea (mg/dL)58.0±41.4613–180
Serum creatinine (mg/dL)1.47±0.860.27–3.75
Serum ammonia (μg/dL)151.55±93.2943–381
ALP – alkaline phosphatase elevation; ALT – alanine aminotransferase; AST – aspartate aminotransferase; INR – international normalized ratio; MELD – model for end-stage liver disease; SD – standard deviation; TB – total bilirubin; WBC – white blood cell.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358