08 June 2021 : Original article
Application of Metagenomic Next-Generation Sequencing to Diagnose Pneumocystis jirovecii Pneumonia in Kidney Transplantation Recipients
Jia Xu12345ABCDEF, Yedong Yu12345ABCD, Junhao Lv12345ABCD, Sisi Yang6ABCD, Jianyong Wu12345AD, Jianghua Chen12345AD, Wenhan Peng12345AEFG*DOI: 10.12659/AOT.931059
Ann Transplant 2021; 26:e931059
Table 2 Reads of each pathogen in the mNGS.
| Recipients | Sample | Bacterium | Fungus | Virus | Others* | ||||
|---|---|---|---|---|---|---|---|---|---|
| Streptococus | Pneumocytis | HSV1 | EBV | CMV | HSV7 | Human parvovirus B19 | |||
| 1 | BALF | – | 155790 | – | – | – | – | – | – |
| PB | – | 1325 | 40 | 7 | 5 | – | – | – | |
| 2 | BALF | – | 1041285 | – | – | – | – | – | – |
| 3 | BALF | – | 607 | 172 | 96 | 467 | – | – | – |
| 4 | BALF | 16539 | 25370 | – | 3188 | 186 | – | – | – |
| 5 | BALF | – | 35754 | – | – | 55 | 15 | – | – |
| 6 | BALF | – | 238 | – | 21 | 6 | – | – | – |
| 7 | BALF | – | 98273 | – | 47 | 47 | – | – | – |
| 8 | PB | – | 19 | – | – | – | – | – | – |
| 9 | BALF | – | 257620 | – | – | – | – | – | – |
| PB | – | 301 | – | – | 9 | – | – | – | |
| 10 | BALF | – | 1033 | – | – | – | – | 3228 | – |
| 11 | BALF | – | 58223 | – | – | 93 | – | – | – |
| 12 | BALF | – | 4307 | – | – | – | – | – | – |
| PB – peripheral blood; BALF – bronchoalveolar lavage fluid; HSV1 – human alpha herpesvirus 1; EBV – human gamma herpesvirus 4; CMV – human beta herpesvirus 5; HSV7 – human herpesvirus 7; * others – parasite, mycobacterium tuberculosis, mycoplasma, chlamydia, rickettsia; ‘−’ – negative. | |||||||||