08 June 2021 : Original article
Application of Metagenomic Next-Generation Sequencing to Diagnose Pneumocystis jirovecii Pneumonia in Kidney Transplantation Recipients
Jia Xu12345ABCDEF, Yedong Yu12345ABCD, Junhao Lv12345ABCD, Sisi Yang6ABCD, Jianyong Wu12345AD, Jianghua Chen12345AD, Wenhan Peng12345AEFG*DOI: 10.12659/AOT.931059
Ann Transplant 2021; 26:e931059
Table 3 Laboratory tests.
| Recipient | Grocott-Gomori stains (BALF) | Cryptococcus neoformans capsular polysaccharide antigen (PB) | BG (PB, pg/ml) | GM (PB) | Culture (BALF) | Culture (PB) | ||
|---|---|---|---|---|---|---|---|---|
| 1 | + | − | 235 | 0.99 | − | − | ||
| 2 | + | − | 559 | 0.55 | − | − | ||
| 3 | + | − | 773 | 1.39 | − | − | ||
| 4 | − | − | 598 | <0.25 | − | − | ||
| 5 | − | − | 623 | 0.29 | − | − | ||
| 6 | − | − | 324 | 0.17 | − | − | ||
| 7 | + | − | 507 | <0.25 | − | − | ||
| 8 | n/a | − | 768 | 0.13 | n/a | − | ||
| 9 | + | − | 115 | 0.24 | − | − | ||
| 10 | + | − | 729 | 0.17 | − | − | ||
| 11 | + | − | 1000 | <0.25 | − | − | ||
| 12 | + | − | 390 | 0.18 | − | − | ||
| 1 | − | − | 0.24 | 44.3 | 8.5 | 96.4 | ||
| 2 | − | − | 0.82 | 23.3 | 4.6 | 86.6 | ||
| 3 | − | − | n/a | 33.7 | 2.7 | 72.6 | ||
| 4 | − | − | 1.53 | 52 | 9.2 | 92.2 | ||
| 5 | − | − | 0.16 | 61.8 | 10.2 | 81.4 | ||
| 6 | − | − | 0.05 | 1 | 7.3 | 77.7 | ||
| 7 | − | − | 0.23 | 32.2 | 10.4 | 87.5 | ||
| 8 | n/a | n/a | 0.15 | 85 | 16.6 | 83.9 | ||
| 9 | − | − | 0.27 | 116.1 | 5.7 | 70.6 | ||
| 10 | − | − | 0.15 | 13.9 | 3 | 66.1 | ||
| 12 | − | − | 0.15 | 84.2 | 5.2 | 84.4 | ||
| 12 | − | − | 0.12 | 72.2 | 12.3 | 73.3 | ||
| 1 | 0 | 12 | 13.9 | 40 | 45.7 | 0.3 | 314 | 281 |
| 2 | 0 | 109 | 28.9 | 209 | 55.1 | 0.52 | 296 | 297 |
| 3 | 0 | 183 | 26.9 | 205 | 30 | 0.89 | 374 | 299 |
| 4 | 0 | 77 | 28.4 | 107 | 39.6 | 0.72 | 193 | 140 |
| 5 | 0.6 | 84 | 18.4 | 151 | 32.9 | 0.56 | 166 | 155 |
| 6 | 0.1 | 113 | 24.7 | 114 | 24.8 | 0.99 | 181 | 145 |
| 7 | 1.2 | 220 | 53.4 | 113 | 27.4 | 1.95 | 165 | 135 |
| 8 | 1 | 705 | 48.7 | 488 | 33.7 | 1.44 | 128 | 183 |
| 9 | 0.5 | 55 | 24.9 | 100 | 45.4 | 0.55 | 411 | 317 |
| 10 | 5 | 234 | 36.4 | 372 | 57.9 | 0.63 | 150 | 188 |
| 12 | 1.5 | 296 | 54.9 | 130 | 24.2 | 2.27 | 267 | 330 |
| 12 | 0.6 | 1197 | 46.9 | 611 | 23.9 | 1.96 | 184 | 178 |
| PB – peripheral blood; BALF – bronchoalveolar lavage fluid; BG – β-d-glucan assays; GM – serum galactomannan assays; PCT – procalcitonin; CRP – C-reactive protein; ESR – erythrocyte sedimentation rate; WBC – white blood cell; Neut – neutrophil; Eo – eosinophilia; Th – helper T cell; Tc – cytotoxic T lymphocyte; SCr1 – serum creatinine before hospitalization; SCr2 – serum creatinine after hospitalization; n/a – not available; ‘+’ – positive; ‘−’ – negative. | ||||||||