Identification of High-Mobility Group Box 1 (HMGB1) Expression as a Potential Predictor of Rejection and Poor Prognosis After Liver Transplantation

20 July 2021 : Original article

Zhou Ye^12ABEF, Junjun Jia^12FG, Zhen Lv^12BCF, Shusen Zheng^12AG*

DOI: 10.12659/AOT.931625

Ann Transplant 2021; 26:e931625

Table 2 Characteristics of recipients between the HMGB1 high-expression group and low-expression group.

HMGB1 expression level	High expression (n=38)	Low expression (n=75)	P value
Age	42.6±9.89	43.2±9.93	NS

Sex (Male/Female)	34/4	61/14	NS

Child-Pugh scores	10.0±2.17	9.7±2.10	NS

MELD scores	23.6±10.27	21.7±9.50	NS

Rejection (n)	26	36	0.039
Non-rejection (n)	12	39	0.039
NS – no significance; HMGB1 – high-mobility group box 1; MELD – model for end-stage liver disease.