Immunological Results of Long-Term Use of Mammalian Target of Rapamycin (mTOR) Inhibitors and Its Effects on Renal Graft Functions

Mehmet Tanrısev; Tülay Ayna Kılıçaslan; Hülya Çolak; Sibel Ersan; Banu Yılmaz; Alper Alp; Cem Tuğmen; Bahar Engin Sevgili

doi:10.12659/AOT.932434

17 September 2021 : Original article

Immunological Results of Long-Term Use of Mammalian Target of Rapamycin (mTOR) Inhibitors and Its Effects on Renal Graft Functions

Mehmet Tanrısev^1ABCDEF*, Tülay Ayna Kılıçaslan^2CD, Hülya Çolak^1BFG, Sibel Ersan^1BD, Banu Yılmaz^1BFG, Alper Alp^3B, Cem Tuğmen^4BC, Bahar Engin Sevgili

^5E

DOI: 10.12659/AOT.932434

Ann Transplant 2021; 26:e932434

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Table 2 Biochemical analysis features of the study groups.

Variables	mTOR group (n=37) mean±SD	CNI group (n=52) mean±SD	p
Post-transplant creatinine (mg/dl)	1.20±0.3	1.30±0.3	0.060
Actual creatinine (mg/dl)	1.32±0.5	1.43±0.5	0.330
Post-transplant eGFR (ml/min per/1.73 m)	67.4±16	63±12.8	0.230
Actual eGFR (ml/min per/1.73 m)	59.7±20	57±17	0.520
Post-transplant spot urine protein/creatinine	0.1±0.2	0.14±0.3	0.110
Actual spot urine protein/creatinine	0.3±0.5	0.28±1.0
Independent t test was used and P

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Immunological Results of Long-Term Use of Mammalian Target of Rapamycin (mTOR) Inhibitors and Its Effects on Renal Graft Functions

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