05 October 2021 : Original article
Wilson Disease in Children; Chelation Therapy or Liver Transplantation? A 10-Year Experience from Pakistan
Sahira Aaraj1CDE*, Sabeen Abid Khan
1DF, Naurin Ali1BF, Munir I. Iqbal Malik2ADF, Faisal Saud Dar3AF
DOI: 10.12659/AOT.932606
Ann Transplant 2021; 26:e932606
Table 2 Demographic, clinical, and laboratory data of patients with Wilson disease.
| Group 1Oral chelationn=34 | Group 2Liver transplantn=11 | Group 3Asymptomaticn=3 | |
|---|---|---|---|
| Age in years | 9.83 [–]5 | 9.45 [–]5 | 5 |
| Male: Female | 21: 13 | 7: 4 | 0: 3 |
| Hepatic involvement(number) | 17 | 11 | None |
| KF rings number (number) | 19 | 8 | Absent in all |
| Coombs negative hemolytic anemia (number) | 18 | 7 | Absent in all |
| Low Serum ceruloplasmin | 20 | 10 | 3 |
| Urine copper μmole/24hours | 482.26 (104–2124) | 721.6 (145–2172) | 499 (216–856) |