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05 October 2021: Original Paper

Wilson Disease in Children; Chelation Therapy or Liver Transplantation? A 10-Year Experience from Pakistan

Sahira Aaraj 1CDE* , Sabeen Abid Khan 1DF , Naurin Ali 1BF , Munir I. Iqbal Malik 2ADF , Faisal Saud Dar 3AF

DOI: 10.12659/AOT.932606

Ann Transplant 2021; 26:e932606

Table 4 King’s Wilson indices of individual patients with Wilson disease.

Group 1Oral chelationn=34Group 2Liver transplantn=11Group 3Asymptomaticn=3
Bilirubin (μmol/L)5.30 (0.20–51.13)11.8 (1.1–30.9)0.473 (0.36–0.58)
INR1.58 (1–4.8)3.5 (1.1–8.02)1.33 (1.05–1.09)
Albumin (g/L)3.1 (1.5–4.8)2.62 (1.6–3.7)2.8 (2.2–3.2)
ALT (IU/L)101.6 (10–674)121.36 (47–327)31 (27–34)
AST (IU/L)103.80 (18–434)134.45 (38–280)39.3 (30.9–46)
ALP (IU/L)328.46 (13–1198)233.3 (92–849)616 (194–1451)
Hb (g/L)11.4 (6–14.6)11.04 (8.30–13.9)11.2 (10.4–12.4)
Leucocyte count (10/L)7215.75 (1750–20700)8624.54 (1200–15600)7400 (6200–9000)
Kings Wilsons Index5.34 (1–14)11 (6–14)4 (2–6)

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358