01 October 2021 : Original article
Outcomes After Living Donor Liver Transplantation in Pediatric Patients with Inherited Metabolic Diseases
Yukihiro Sanada1ABCDEF*, Yasunaru Sakuma1DF, Yasuharu Onishi1B, Noriki Okada1B, Naoya Yamada1B, Yuta Hirata1B, Go Miyahara1B, Takumi Katano1B, Toshio Horiuchi1B, Takahiko Omameuda1B, Alan Kawarai Lefor
1DF, Naohiro Sata1DF
DOI: 10.12659/AOT.932994
Ann Transplant 2021; 26:e932994
Table 5 Post-transplant survival rates of patients with IMDs.
| Institutions | Number of patients | Survival | Complications or others |
|---|---|---|---|
| McKiernan PJ (2019) []SRTR1 | 2354 (17%) | 5-year graft: 94.5% | |
| Kim JS (2015) []Asan Medical Center2 | 54 (1.6%) | 1-year graft: 88.8%5-year graft: 85.5%10-year graft: 85.5% | |
| Mazariegos G (2014) []Children’s Hospital of Pittsburgh3 | 285 | 1-year graft: 79.3%5-year graft: 73.1%10-year graft: 67.4%20-year graft: 56.9% | |
| Kasahara M (2014) []Japan registry4 | 194 (8.7%) | 1-year graft: 91.2%5-year graft: 87.9%10-year graft: 86.1%15-year graft: 74.4% | |
| Arnon R (2010) []SPLIT registry5 | 446 (14.9%) | 1-year graft: 90.8%5-year graft: 83.8% | |
| Stevenson T (2010) []Stanford University6 | 54 | recipient: 100%(Observation period: 5.4±4.4 year) | |
| Sze YK (2009) []King’s college Hospital7 | 96 (16.7%) | 1-year graft: 83%5-year graft: 77%10-year graft: 62% | |
| Morioka D (2005) []Kyoto University8 | 46 (8.0%) | 1-year recipient: 86.8%5-year recipient: 81.2%10-year recipient: 81.2% | |
| Kayler LK (2003) []UNOS9 | 551 (20.2%) | 1-year recipient: 94%5-year recipient: 92% | |
| Our studyJichi Meidcal University | 44 (14.0%) | 1-year graft: 90.9%5-year graft: 90.9%10-year graft: 87.1% | |
| IMDs – inherited metabolic diseases; SRTR – the Scientific Registry of Transplant Recipients; LT – liver transplantation; LDLT – living donor liver transplantation; DDLT – deceased donor liver transplantation; UCD – urea cycle disorders; MSUD – maple syrup urine disease; UNOS; the United Network for Organ Sharing. | |||