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19 November 2021: Original Paper

Diagnostic Utility of Presepsin in Infections After Liver Transplantation: A Preliminary Study

Takahiro Yokose 1ABCDEF* , Masashi Takeuchi 1ABCDEF* , Hideaki Obara 1ACDEFG* , Masahiro Shinoda 2ADF , Hirofumi Kawakubo 1ADF , Minoru Kitago 1BCD , Hiroshi Yagi 1BCD , Yuta Abe 1BCD , Yohei Yamada 1BCD , Kentaro Matsubara 1BCD , Go Oshima 1BCD , Shutaro Hori 1BCD , Takumi Fujimura 1BCD , Ryo Takemura 3CD , Ryota Ishii 3CD , Tatsuo Kuroda 1A , Yuko Kitagawa 1AG

DOI: 10.12659/AOT.933774

Ann Transplant 2021; 26:e933774

Table 1 Patient characteristics.

Variables, (%)Total (n=13)
Recipient age, years* 44 (38–55)
Body mass index, kg/m* 20.3 (19.2–24.0)
Sex, Male/Female4 (30.8) / 9 (69.2)
ASA-PS, 2 / 3 / 42 (15.4) / 7 (53.8) / 4 (30.8)
ECOG-PS, 0 / 1 / 2 / 31 (7.7) / 4 (30.8) / 5 (38.5) / 3 (23.1)
Primary disease
 Alcohol-related liver disease4 (30.8)
 Primary biliary cholangitis3 (23.1)
 Primary sclerosing cholangitis2 (15.4)
 Autoimmune hepatitis2 (15.4)
 Hepatopulmonary syndrome1 (7.7)
 Unknown1 (7.7)
Child-Pugh score* 12 (11–13)
MELD score* 25 (18–32)
Creatinine clearance* 68.1 (40.8–98.5)
Donor type
 Living / deceased7 (53.8) / 6 (46.2)
Donor age, years* 44 (31–52)
ABO blood type
 Identical / Compatible / Incompatible9 (69.2) / 2 (15.4) / 2 (15.4)
Donor Liver
 Left lobe / Right lobe / Whole liver7 (53.8) / 1 (7.7) / 5 (38.5)
Intraoperative bleeding, ml* 2760 (1415–5583)
Operation time, min* 774 (708–913)
Bile duct reconstruction
Hepaticocholedochostomy / Hepaticojejunostomy11 (84.6) / 2 (15.4)
Postoperative acute kidney injury9 (69.2)
Postoperative continuous renal replacement therapy4 (30.8)
* Median (25–75 percentiles).
ASA – American Society of Anesthesiologists; PS – performance status; ECOG – Eastern Cooperative Oncology Group; MELD – model for end-stage liver disease.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358