Diagnostic Utility of Presepsin in Infections After Liver Transplantation: A Preliminary Study

Takahiro Yokose; Masashi Takeuchi; Hideaki Obara; Masahiro Shinoda; Hirofumi Kawakubo; Minoru Kitago; Hiroshi Yagi; Yuta Abe; Yohei Yamada; Kentaro Matsubara; Go Oshima; Shutaro Hori; Takumi Fujimura; Ryo Takemura; Ryota Ishii; Tatsuo Kuroda; Yuko Kitagawa

doi:10.12659/AOT.933774

19 November 2021 : Original article

Diagnostic Utility of Presepsin in Infections After Liver Transplantation: A Preliminary Study

Takahiro Yokose^1ABCDEF, Masashi Takeuchi^1ABCDEF, Hideaki Obara^1ACDEFG*, Masahiro Shinoda^2ADF, Hirofumi Kawakubo^1ADF, Minoru Kitago

^1BCD, Hiroshi Yagi^1BCD, Yuta Abe^1BCD, Yohei Yamada^1BCD, Kentaro Matsubara^1BCD, Go Oshima^1BCD, Shutaro Hori^1BCD, Takumi Fujimura^1BCD, Ryo Takemura^3CD, Ryota Ishii^3CD, Tatsuo Kuroda^1A, Yuko Kitagawa^1AG

DOI: 10.12659/AOT.933774

Ann Transplant 2021; 26:e933774

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Table 3 Comparison of changes in presepsin, procalcitonin, and C-reactive protein levels and leukocyte count between the infection and non-infection groups.

	Presepsin (pg/mL)			Procalcitonin (ng/mL)
	Non-infection group	Infection group	p	Non-infection group	Infection group	p
	(n=8)	(n=5)	p	(n=8)	(n=5)	p
Baseline	668 (396–2559)	624 (289–2144)	0.833	0.16 (0.11–0.27)	0.31 (0.12–0.42)	0.435
POD 0	1755 (619–2899)	1613 (1134–3425)	0.435	1.16 (0.55–2.66)	1.20 (1.11–3.96)	0.622
POD 1	1594 (546–2968)	1420 (930–3179)	0.622	1.95 (0.97–4.73)	3.94 (2.13–4.11)	0.435
POD 2	1144 (449–2896)	1896 (1736–2961)	0.284	2.28 (1.14–5.06)	8.56 (4.31–8.90)	0.222
POD 3	960 (400–1942)	2406 (2262–2469)	0.127	1.26 (0.81–3.46)	5.33 (3.75–7.37)	0.171
POD 5	903 (431–1300)	2188 (1970–2474)	0.019	0.83 (0.62–1.39)	2.27 (1.37–4.72)	0.354
POD 7	888 (682–1335)	2659 (1788–4767)	0.011	0.75 (0.56–1.52)	1.64 (0.84–2.46)	0.524



Baseline	0.63 (0.20–1.00)	0.73 (0.31–3.06)	0.435	3.7 (2.7–5.8)	5.3 (4.5–5.5)	0.284
POD 0	0.20 (0.12–1.77)	2.18 (0.33–3.32)	0.171	4.3 (3.6–5.2)	6.8 (4.0–10.3)	0.222
POD 1	1.05 (0.59–4.75)	4.48 (1.07–6.48)	0.435	4.1 (2.8–6.2)	4.8 (4.3–7.3)	0.222
POD 2	3.07 (1.14–4.11)	3.60 (3.29–3.74)	0.622	9.4 (5.4–12.9)	5.9 (5.8–9.0)	0.833
POD 3	1.43 (0.84–2.13)	1.79 (1.71–2.06)	0.354	8.8 (7.4–10.6)	5.1 (4.6–10.5)	0.435
POD 5	0.37 (0.15–0.54)	0.50 (0.42–0.97)	0.354	7.2 (5.3–7.8)	4.9 (3.3–7.6)	0.622
POD 7	0.24 (0.19–0.56)	0.46 (0.39–0.53)	0.354	7.8 (4.8–10.7)	5.2 (4.3–9.5)	0.524

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Diagnostic Utility of Presepsin in Infections After Liver Transplantation: A Preliminary Study

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