Impact of Thyroid Incidentaloma on Liver Transplant: A Study of 1010 Recipients at a Single Center

08 February 2022: Original Paper

Yi-Chia Chan ^12ABCE , Chao-Long Chen ^12A , Chih-Che Lin ^12A , Chee-Chien Yong ^12BDE , Yi-Ju Wu ^12BDE , Shun-Yu Chi ^2AEF* , Fong-Fu Chou ^2A

DOI: 10.12659/AOT.934988

Ann Transplant 2022; 27:e934988

Table 1 Patient characteristics in liver cirrhotic patients waiting for liver transplantation.

	Enhanced chest CT (n=1010)			18F-FDG PET (n=498)
	CT thyroid incidentaloma (n=23, 2.3%)	No CT thyroid incidentaloma (n=987)	P value	PET thyroid incidentaloma (n=15, 3.0%)	No PET thyroid incidentaloma (n=483)	P value
	58 (53–65)	55 (50–60)	0.061	55 (52–64)	55 (50–61)	0.233
	10 (43.5%)	276 (28.0%)	0.103	10 (66.7%)	349 (72.3%)	0.635
	26.6 (22–28)	24.9 (23–27)	0.405	23 (21–27)	25.2 (23–28)	0.149
	14 (9–20)	12 (8–17)	0.397	8 (7–14)	12 (9–16)	0.080
	9 (7–10)	8 (6–10)	0.114	7 (5–9)	8 (6–10)	0.066
	3 (13.6%)	143 (16.3%)	0.736	2 (13.3%)	86 (19.1%)	0.577
	8 (36.4%)	209 (23.8%)	0.172	2 (13.3%)	116 (25.6%)	0.281
	11 (47.8%)	472 (47.8%)	1.000	10 (66.7%)	253 (52.4%)	0.275
,^*
HBV hepatitis	10 (43.5%)	453 (45.9%)	0.818	7 (46.7%)	212 (43.9%)	0.831
HCV hepatitis	6 (26.1%)	301 (30.5%)	0.649	4 (26.7%)	157 (32.5%)	0.634
Alcoholism	5 (21.7%)	202 (20.5%)	0.881	2 (13.3%)	111 (23.0%)	0.380
Autoimmune hepatitis	2 (8.7%)	37 (3.7%)	0.225	1 (6.7%)	5 (1.0%)	0.049
Others^**	3 (13%)	68 (6.9%)	0.254	1 (6.7%)	32 (6.6%)	1.000

2-year patient survival rate	76%	91%	0.231	80%	87%	0.238
Data are shown as the median (interquartile range (IQR) 25–75) and number (%) ^* Some patients were diagnosed with combined viral hepatitis (ex: HBV+HCV) or viral hepatitis with alcoholism (HBV+alcoholism or HCV+alcoholism). ^** Others include cryptogenic liver cirrhosis, Wilson’s disease, polycystic liver kidney disease, Budd-Chiari syndrome…etc. BMI – body mass index, HCC – hepatocellular carcinoma, MELD – model for end-stage liver disease.