03 May 2022 : Original article
Outcomes of Split Liver Transplantation vs Living Donor Liver Transplantation in Pediatric Patients: A 5-Year Follow-Up Study in Korea
Kyung Chul Yoon12ABCDEF, Sanghee Song3BC, Sanghoon Lee4BC, Ok-Kyung Kim3BC, Suk Kyun Hong1BC, Nam-Joon Yi1ABCDEF, Jong Man Kim4BCD, Kwang-Woong Lee1ABCD, Myoung Soo Kim5BCD, YoungRok Choi1BCD, Kyung-Suk Suh1ABCD, Suk-Koo Lee4ACDEF*DOI: 10.12659/AOT.935682
Ann Transplant 2022; 27:e935682
Table 1 Demographics of donors and recipients in the SLT versus LDLT groups.
| Categorical value | SLT (n=63) | LDLT (n=56) | P-value | |
|---|---|---|---|---|
| Age (Years) | Median (IQR) | 1.4 (0.9–2.8) | 1.0 (0.8–7.8) | 0.47 |
| ≤1 year, n (%) | 23 (40.4) | 34 (63.5) | <0.01 | |
| Sex, n (%) | Male | 22 (34.9) | 31 (55.4) | 0.03 |
| Body weight (kg) | Median (IQR) | 10.0 (7.2–13.0) | 14.6 (10.2–25.4) | <0.01 |
| ≤10 kg, n (%) | 34 (54.0) | 13 (23.2) | <0.01 | |
| Diagnosis, n (%) | Biliary atresia | 38 (60.3) | 38 (67.9) | 0.07 |
| Malignant | 2 (3.2) | 3 (5.4) | ||
| Fulminant | 1 (1.6) | 5 (8.9) | ||
| Others | 22 (34.%) | 10 (17.9) | ||
| KONOS Status, n (%)* | 1 | 5 (7.9) | 4 (8.0) | 0.35 |
| 3 | 36 (57.1) | 22 (44.0) | ||
| 4 | 22 (34.9) | 48 (48.0) | ||
| Laboratory PELD score | Mean | 15.5±12.1[Missing 7, (11.1%)] | 16.2±13.7 | 0.76 |
| Total ischemic time (min) | Mean | 256±163 [Missing 7, (11.1%)] | 102±40 [Missing 5, (8.9%)] | <0.01 |
| >300 min, n (%) | 19 | 0 | <0.01 | |
| Graft weight (g) | Mean | 345 (283–410) [Missing 9, 14.2%)], | 297 (257–368) [Missing 2, (3.5%)] | 0.69 |
| GRWR (%) | Mean | 3.83±1.7 [Missing 9, (14.2%)] | 2.44±1.36 [Missing 2 (3.5%)] | <0.01 |
| Follow up period (Month) | Mean | 44±30 | 74±40 | <0.01 |
| Age (Years) | Mean | 24.9±7.7 | 34.6±6.4 | <0.01 |
| >40 year, n (%) | 1 (1.6) | 14 (25.0) | <0.01 | |
| Sex | Male | 44 (69.8) | 26 (46.4) | 0.02 |
| Body weight (kg) | Median (IQR) | 63 (55–75) | 63 (57–69) | 0.87 |
| * KONOS status similar to the UNOS status is available in as described in the introduction. IQR – Interquartile range; KONOS – Korean network for organ sharing; LLS – left lateral section; SLT – split liver transplantation; LDLT – living donor liver transplantation. | ||||