Clinical Validation of a Novel Scoring System Based on Donor and Recipient Risk Factors for Predicting Outcomes in Liver Transplantation

Lucas Souto Nacif; Daniel Reis Waisberg; Leonardo Yuri Zanini; Rafael Soares Pinheiro; Vinicius Rocha-Santos; Rubens Arantes Macedo; Liliana Ducatti; Luciana Haddad; Rodrigo Bronze de Martino; Flávio Galvão; Wellington Andraus; Luiz Carneiro-D‘Albuquerque

doi:10.12659/AOT.936271

30 August 2022 : Original article

Clinical Validation of a Novel Scoring System Based on Donor and Recipient Risk Factors for Predicting Outcomes in Liver Transplantation

Lucas Souto Nacif^1ABCDEF*, Daniel Reis Waisberg^1CDE, Leonardo Yuri Zanini^1BCDEF, Rafael Soares Pinheiro^1ACD, Vinicius Rocha-Santos^1ACD, Rubens Arantes Macedo^1BD, Liliana Ducatti

^1BD, Luciana Haddad^1BD, Rodrigo Bronze de Martino^1ACDE, Flávio Galvão^1AD, Wellington Andraus^1ACD, Luiz Carneiro-D‘Albuquerque^1AD

DOI: 10.12659/AOT.936271

Ann Transplant 2022; 27:e936271

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Table 3 COX regression analysis (30% bank randomly selected).

	Coefficient	Risk	SD	IC 95%	Wald teste	p-value
Cardiopulmonary arrest >5 minutes	−0.80	0.45	0.29	(0.25–0.8)	7.3	0.007
≥7 days ICU (donor)	0.63	1.90	0.23	(1.20–3.00)	7.4	0.007
Fulminant hepatitis	0.96	2.60	0.31	(1.40–4.80)	9.3	0.002
MELD (24–29)	0.93	2.526	0.347	(1.28–4.98)	23.06	0.008
MELD (29–35)	0.72	2.056	0.255	(1.04–4.06)	23.06	0.038
MELD (>35)	1.59	4.915	0.282	(2.83–8.54)	23.06	<0.001
Creatinine before transplant >1.5 mg/dL	1.20	3.40	0.23	(2.10–5.30)	28	<0.001
SD – standard deviation; IC – confidence index; ICU – Intensive Care Unit; MELD – model of end stage liver disease. log-rank demonstrated p

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Clinical Validation of a Novel Scoring System Based on Donor and Recipient Risk Factors for Predicting Outcomes in Liver Transplantation

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