Clinical Validation of a Novel Scoring System Based on Donor and Recipient Risk Factors for Predicting Outcomes in Liver Transplantation

Lucas Souto Nacif; Daniel Reis Waisberg; Leonardo Yuri Zanini; Rafael Soares Pinheiro; Vinicius Rocha-Santos; Rubens Arantes Macedo; Liliana Ducatti; Luciana Haddad; Rodrigo Bronze de Martino; Flávio Galvão; Wellington Andraus; Luiz Carneiro-D‘Albuquerque

doi:10.12659/AOT.936271

30 August 2022 : Original article

Clinical Validation of a Novel Scoring System Based on Donor and Recipient Risk Factors for Predicting Outcomes in Liver Transplantation

Lucas Souto Nacif^1ABCDEF*, Daniel Reis Waisberg^1CDE, Leonardo Yuri Zanini^1BCDEF, Rafael Soares Pinheiro^1ACD, Vinicius Rocha-Santos^1ACD, Rubens Arantes Macedo^1BD, Liliana Ducatti

^1BD, Luciana Haddad^1BD, Rodrigo Bronze de Martino^1ACDE, Flávio Galvão^1AD, Wellington Andraus^1ACD, Luiz Carneiro-D‘Albuquerque^1AD

DOI: 10.12659/AOT.936271

Ann Transplant 2022; 27:e936271

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Table 4 COX regression analysis (validation group – 70% bank randomly selected).

	Coefficient	Risk	SD	IC 95%	Wald teste	p-value
Retransplant	−17	1.60	0.29	3.6e-08 (0-Inf)	0	0.99
Fulminant hepatitis	0.66	0.20	0.23	1.90 (1.30–2.90)	11	<0.001
Large surgery/biliary tree surgery	0.45	0.21	0.21	1.60 (1.10–2.40)	4.9	0.03
MELD (24–29)	0.26	1.30	0.77	1.30 (0.70–2.23)	25.6	0.34
MELD (29–35)	0.51	1.66	0.60	1.66 (1.12–2.46)	25.6	0.01
MELD (>35)	0.90	2.46	0.41	2.46 (1.72–3.54	25.6	<0.001
Creatinine before transplant >1.5 mg/dL	0.77	0.15	0.46	2.20 (1.60–2.90)	26	<0.001
SD – standard deviation; IC – confidence index; MELD – model of end stage liver disease. Log-rank demonstrated p

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Clinical Validation of a Novel Scoring System Based on Donor and Recipient Risk Factors for Predicting Outcomes in Liver Transplantation

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