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26 August 2022: Original Paper

Development of a Novel Model for Predicting Postoperative Short-Term Outcome in Patients with Hepatitis B-Related Acute-on-Chronic Liver Failure Undergoing Liver Transplantation

Qikun Zhang 12ABCDEF , Menglong Wang 2ADF , Guangming Li 2BDG , Zhongtao Zhang 1ADE*

DOI: 10.12659/AOT.936732

Ann Transplant 2022; 27:e936732

Supplementary Table 1 The formula of 16 scoring models.

ModelsFormula (parameter)
CTP(Child-Pugh)Bilirubin, Albumin, Prothrombin time, Encephalopathy, Ascites
UNOS-MELD(0.957×Loge[creatinine mg/dl]+0.378×Loge[total bilirubin mg/dl]+1.120×Loge[INR]+ 0.643)×10
Updated-MELD1.266 loge(1+creatinine)+0.939 loge(1+bilirubin)+1.658 loge(1+INR)
MELD-NaMELD+1.59×(135-Na) (Na 120mmo/L~135 mmo/L)
MLED NaMELD−Na−[0.025×MELD×(140−Na)]+140 (Na 125 mmo/L~140 mmo/L)
CLIF-SOFARespiration (PaO/FiO or SpO/FiO), Coagulation (INR), Liver (Bilirubin), Cardiovascular (MAP/dopamine or dobutamine or terlipressin or epinephrine or norepinephrine), CNS (HE grade), Renal (Creatinine)
CLIF-OFsLiver (bilirubin), Kidney (creatinine), Brain (West-Haven grade for HE), Coagulation (INR), Circulatory (MAP/use of vasopressors), Respiratory (PaO/FiO or SpO/FiO)
CLIF-C ACLFs10×[0.33×CLIF-OFs+0.04×Age+0.63×In (WBC count)-2]
CLIF-C ADs10×0.03×Age(years)+0.66×Ln(Creatinine(mg/dL))+1.71×Ln(INR)+0.88×In(WBC(10 cells/L))−0.05× Sodium (mmol/L)+8
Refit MELD4.082×Loge (bilirubinc)+8.485×Loge (creatiinec)+10.671×Loge (INRC)+7.432
Refit MELD Na4.258×Loge (bilirubinc)+6.792 Loge (creatiinec)+8.290×Loge (INRC)+0.652×(140-Nac)-0.194× (140-Nac)×Bilicc+6.327
Zheng’s Risk−2.3090+0.3600×Creatinine (mg/dl)+0.5493×(need for hemodialysis [0, 1])+0.7000×(moderate ascites [0, 1])
UKELD[(5.395×Ln(INR))+(1.485×Ln (creatinine))+(3.130×Ln (bilirubin))−(81.565×Ln (sodium))]+435
MESO(MELD Score/Serum Sodium)×10

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358