27 September 2022 : Original article
Using Postoperative Coagulation Parameters Within 24 h After Liver Transplantation to Predict Incidence of Stage 3 Acute Kidney Injury (AKI)
Chen Chen1BCD, Xiaolan Chen2BC, Xianyuan Zhao1D, Junqi Feng1E, Yuan Gao1E, Yuxiao Deng
1EF, Zhe Li1EF*
DOI: 10.12659/AOT.937535
Ann Transplant 2022; 27:e937535
Table 1 Demographic and pre-and intraoperative clinical data of the studied population (n=241).
| Groupn | AKI stage 0–2213 | AKI stage 328 | P value |
|---|---|---|---|
| Male (n, %) | 155 (72.8) | 20 (71.4) | 0.881 |
| Age [mean±SD, y] | 50.7±10.9 | 52.5±11.8 | 0.508 |
| AKI stage 3 requiring CRRT (n, %) | 0 (0) | 6 (21.4) | <0.001 |
| Etiology of liver transplantation | |||
| cirrhosis | |||
| Hepatitis B (n, %) | 40 (18.8) | 4 (14.3) | 0.556 |
| PBC (n, %) | 13 (6.1) | 1 (3.6) | 0.590 |
| Alcoholic (n, %) | 11 (5.2) | 0 (0) | 0.218 |
| AIH (n, %) | 13 (6.1) | 3 (10.7) | 0.357 |
| Other (n, %) | 12 (5.6) | 3 (10.7) | 0.296 |
| Liver cancer (n, %) | 96 (45.1) | 10 (35.7) | 0.097 |
| hepatic failure (n, %) | 39 (18.3) | 12 (43.9) | 0.003 |
| Other (n, %) | 4 (1.8) | 0 (0) | 0.419 |
| Ascites [ (, ), mL] | 200 (0, 1500) | 200 (0, 2000) | 0.893 |
| MELD score [ (, )] | 13 (9, 21) | 17 (11, 32) | 0.006 |
| Bleeding [ (, ), mL] | 500 (400, 800) | 800 (500, 1000) | 0.023 |
| RBC suspension infusion [ (, ), u] | 4 (0, 8) | 8 (4,1 0) | 0.004 |
| Plasma infusion [ (, ), mL] | 400 (0, 1000) | 850 (400, 1300) | 0.010 |
| Hospital mortality (n, %) | 7 (3.3) | 12 (42.9) | <0.001 |
| AKI – acute kidney injury; CRRT – continuous renal replacement therapy; PBC – primary biliary cirrhosis; AIH – autoimmune hepatitis; MELD – model for end stage liver disease; RBC – red blood cell; ALT – alanine transaminase; AST – aspartate transaminase; TB – total bilirubin; INR – international normalized ratio; FDP – fibrinogen degradation products; HB – hemoglobin; PLT – platelet; Scr – creatinine. | |||