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27 September 2022 : Original article  

Using Postoperative Coagulation Parameters Within 24 h After Liver Transplantation to Predict Incidence of Stage 3 Acute Kidney Injury (AKI)

Chen Chen1BCD, Xiaolan Chen2BC, Xianyuan Zhao1D, Junqi Feng1E, Yuan Gao1E, Yuxiao Deng ORCID logo1EF, Zhe Li1EF*

DOI: 10.12659/AOT.937535

Ann Transplant 2022; 27:e937535

Table 3 Multivariate logistic regression analysis of the incidence of stage 3 AKI after LT.

VariableCrude OR (95% CI)P valueAdjusted OR (95%CI)P value
PLT count0.993 (0.983–1.003)<0.001
ADP-induced PLT aggregation0.953 (0.929–0.978)<0.0010.965 (0.936–0.994)0.020
AA-induced PLT aggregation0.969 (0.949–0.989)0.003
FII1.002 (0.980–1.023)0.885
FV0.950 (0.924–0.977)<0.001
FVII0.982 (0.964–1.001)0.065
FVIII0.989 (0.982–0.997)0.005
FIX0.975 (0.954–0.996)0.022
FX0.994 (0.976–1.012)0.512
INR2.654 (1.562–4.507)<0.001
D-dimer1.004 (1.020–1.060)<0.0011.032 (1.010–1.054)0.004
FDP1.007 (1.003–1.011)<0.001
FIB0.231 (0.106–0.504)<0.001
R-value1.204 (0.107–1.309)<0.0011.168 (1.044–1.307)0.007
K value1.041 (0.981–1.104)0.186
α-angle0.955 (0.924–0.987)0.006
MA0.947 (0.912–0.984)0.005
Setting time1.104 (1.040–1.171)0.001
Clot strength1.000 (.999–1.000)0.042
Protein S0.971 (0.945–0.997)0.028
Protein C0.990 (0.968–1.013)0.410
ATIII0.948 (0.916–0.980)0.002
OR – odds ratio; CI – confidence interval; INR – international normalized ratio; FDP – fibrinogen degradation products; FIB – fibrinogen; PLT – platelet; ATIII antithrombin III; α-angle – rate of clot formation; K value – coagulation value to 20-mm clot; LY 30 – % of clot lysis at 30min; MA – maximum amplitude (maximum strength of clot); R value – reaction value (value to fibrin formation 2-mm clot).ss

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358