03 January 2023: Original Paper
Impact of Autologous Stem Cell Transplantation on Primary Central Nervous System Lymphoma in First-Line and Relapse Settings: A Retrospective Study in China
Jing Liu 1BCDEF* , Haitao Wang 1BCDF* , Xiaohong Li 1B , Yamei Wu 1B , Yuanyuan Ma 1B , Zhenyang Gu 1B , Fei Li 1B , Meng Li 1BD , Jiayuan Guo 2B , Yu Zhao 1B , Quanshun Wang 1B , Jian Bo 1B , Wenrong Huang 1B , Liping Dou 1BD , Yuanbo Liu 3AEF , Daihong Liu 1BD , Xiaoxiong Wu 1ADF* , Chunji Gao 1ADEFG*DOI: 10.12659/AOT.938467
Ann Transplant 2023; 28:e938467
Table 4 Univariate and multivariate analyses of OS and PFS for patients (Cox test).
| Variable | PFS | |||||
|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | |||||
| HR | 95% CI | P | HR | 95% CI | P | |
| Age | 0.77 | 0.27–2.14 | 0.611 | 0.93 | 0.24–3.60 | 0.914 |
| Gender | 2.28 | 0.90–5.82 | 0.084 | 1.27 | 0.40–3.98 | 0.684 |
| ECOG | 1.49 | 0.53–4.19 | 0.452 | 2.60 | 0.73–9.24 | 0.141 |
| Number of lesions | 1.67 | 0.60–4.67 | 0.324 | 1.92 | 0.56–6.64 | 0.301 |
| Diagnostic methods | 0.71 | 0.28–1.83 | 0.481 | 0.69 | 0.21–2.24 | 0.538 |
| Deep structure involvement | 1.39 | 0.46–4.23 | 0.560 | 2.31 | 0.36–14.72 | 0.377 |
| ASCT | 0.16 | 0.05–0.57 | 0.004 | 0.16 | 0.04–0.71 | |
| Early response | 0.16 | 0.06–0.46 | 0.000 | 0.12 | 0.03–0.48 | |
| Age | 1.59 | 0.18–13.75 | 0.674 | 2.49 | 0.10–61.33 | 0.577 |
| Gender | 0.62 | 0.12–3.20 | 0.563 | 0.48 | 0.05–5.07 | 0.544 |
| ECOG | 2.18 | 0.25–18.77 | 0.479 | 3.56 | 0.25–50.31 | 0.347 |
| Number of lesions | 0.47 | 0.09–2.36 | 0.358 | 0.35 | 0.04–2.93 | 0.332 |
| Diagnostic methods | 0.35 | 0.08–1.60 | 0.174 | 0.19 | 0.02–1.63 | 0.130 |
| Deep structure involvement | 1.46 | 0.17–12.85 | 0.733 | 1.78 | 0.02–115.71 | 0.786 |
| ASCT | 0.58 | 0.11–3.12 | 0.524 | 0.22 | 0.02–2.56 | 0.227 |
| Early response | 0.20 | 0.03–1.20 | 0.078 | 0.15 | 0.02–1.20 | 0.074 |
| Age, ≥60 y vs | ||||||