Postoperative Outcomes in 415 Patients Following Liver Transplantation Using Extended Donor Criteria: A Study from a Single Center in Germany

07 April 2023 : Original article

Aladdin Ali Deeb^1ACE*, Utz Settmacher^1D, Johannes Fritsch^1BC, Felix Dondorf^1AD, Oliver Rohland^1F, Falk Rauchfuß^1DE

DOI: 10.12659/AOT.939060

Ann Transplant 2023; 28:e939060

Background Material and Methods Results Discussion Conclusions References

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Table 3 Overview of incidence of study’s endpoints.

Variable	N (%)	Pearson’s χ2 and Fischer’s exact test
Variable	N (%)	EDC	EDC-score	Age	ICU-stay	BMI	sNa	sGOT/sGPT	Viral hepatitis
AF	66 (15.9%)	0.143=0.408	1.250=0.870	0.326=0.330	2.378=0.080	0.060=0.465	2.337=0.121	0.037=0.478	1.85=0.584
AAF	37 (8.9%)	0.597=0.281	4.198=0.380	0.798=0.239	0.285=0.383	0.009=0.538	1.210=0.321	2.317=0.096	0.27=0.611
PNF	12 (2.9%)	3.859=0.063	6.384=0.172	2.649=0.088	0.048=0.527	0.503=0.415	0.368=0.700	0.480=0.345	0.792=0.470
Vascular	25 (6%)	0.210=0.440	2.745=0.601	0.006=0.548	0.629=0.304	0.379=0.351	0.792=0.470	1.782=0.137	0.183=0.454
CAD	29 (7%)	0.103=0.486	1.320=0.858	3.303=0.54	2.610=0.076	0.059=0.487	0.928=0.414	2.031=0.111	0.042=0.536
ITBL	19 (4.6%)	2.576=0.086	3.869=0.424	13.138=0.0004^*	1.617=0.161	0.398=0.405	0.593=0.565	2.180=0.109	0.713=0.320
Other causes	10 (2.4%)	2.737=0.110	3.290=0.511	3.683=0.049^*	0.908=0.304	1.595=0.195	0.305=0.743	0.128=0.530	0.657=0.533
EAD	168 (40.5%)	0.04=0.473	3.142=0.534	2.046=0.092	6.164=0.009^*	2.448=0.077	1.634=0.163	0.284=0.337	0.794=0.250
90d mortality	53 (12.8%)	0.016=0.534	5.511=0.239	0.299=0.349	1.030=0.203	0.277=0.385	0.218=0.533	1.153=0.184	1.248=0.202
AF – allograft failure; AAF – acute allograft failure; PNF – primary nonfunction; CAD – chronic allograft failure; ITBL – ischemic type biliary lesions; EAD – early allograft dysfunction; BMI – body mass index; sNa – serum Sodium; sGOT – serum glutamic oxaloacetic transaminase; sGPT – serum glutamic pyruvic transaminase. ^* Statistical significance.

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