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16 May 2023: Original Paper

Breaking Antimicrobial Resistance: High-Dose Amoxicillin with Clavulanic Acid for Urinary Tract Infections Due to Extended-Spectrum Beta-Lactamase (ESBL)-Producing

Piotr Wilkowski 1ABCDEF , Ewa Hryniewiecka 1BCDEF , Kornelia Jasińska 2BCDEF , Leszek Pączek 1ACDEF , Michał Ciszek 1ABCDEF*

DOI: 10.12659/AOT.939258

Ann Transplant 2023; 28:e939258

Table 3 Antibiotic susceptibility of K. pneumoniae strains in urine cultures.

Case No123456789
AmikacinS≤2S≤2I=4S≤2S≤2S≤2S≤2I=16I=16
Amoxicillin/ClavulanateI=8R=16R≥32R≥32R≥32R≥32R≥32S=8R≥32
AmpicillinR≥32R≥32R≥32R≥32ndR≥32R ≥32R≥32R≥32
CefalexinR≥64R≥64R≥64R≥64R≥32R≥64R≥64R≥64R≥64
CefepimeR=16R≥32R≥32R≥32R≥16R≥32R≥32R≥32R≥32
CefotaximeR≥64R≥64R≥64R≥64R≥32R≥64R≥64R≥64R≥64
CeftazidimeR≥64R=32R≥64R=32R=32R=32R=32R≥64R≥64
CefuroximendR≥64R≥64R≥64R≥32R≥64R≥64R≥64R≥64
Cefuroxime axetilR≥64R≥64R≥64R≥64ndR≥64R≥64R≥64R≥64
CeftriaxonendRRRndRRRR
CiprofloxacinR≥4R=1R≥4R≥4R≥2R=2R≥4R≥4R≥4
ErtapenemS≤0,5S≤0.12S≤0.12S≤0.12S≤0.12S≤0.12S≤0.12S≤0.12S≤0.12
GentamicinR≥16S≤1S≤1S≤1S≤1S≤1S≤1R≥16R≥16
ImipenemS≤0.25SSSS≤0.25SSSS
MeropenemSS≤0.25S≤0.25S≤0.25S≤0.25S≤0.25S≤0.25S≤0.25S≤0.25
NorfloxacinR≥16R=2R≥4R≥16R≥16R=4R≥16R≥16R≥16
Piperacillin/TazobactamR≥128I=16R≥128R≥32R=32I=16R=32R≥32R≥128
Trimethoprim/SulfamethoxazoleR≥320R≥320R≥320R≥320R≥16R≥320R≥320R=160S≤20
S – susceptible; I – intermediate susceptibility; R – resistant; nd – no data.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358