27 June 2023: Original Paper
A 15-Year Retrospective Study of Supportive Extracorporeal Therapies Including Plasma Exchange and Continuous Venovenous Hemodiafiltration of 114 Adults with Acute Liver Failure Awaiting Liver Transplantation
Ilhan Ocak ABCDEFG*DOI: 10.12659/AOT.939745
Ann Transplant 2023; 28:e939745
Table 2 Laboratory values of patients before the first combined supportive extracorporeal therapy and after the last combined supportive extracorporeal therapy.
| Liver transplant* candidate | Recovery ALF* | P values | |
|---|---|---|---|
| Before combined SET | |||
| AST (IU/L) | 1635 (1108) | 2645 (1817) | |
| ALT (IU/L) | 1715 (1142) | 2755 (1947) | |
| Lactate (mmol/L) | 5.75 (1.15) | 6 (2.8) | 0.027 |
| Ammonia (μmol/L) | 128 (28.5) | 132 (46.5) | 0.401 |
| Total bilirubin (mg/dL) | 19.25 (8.18) | 8.2 (3.97) | |
| PT/INR | 3.35 (0.7) | 3.4 (0.77) | 0.156 |
| After combined SET | |||
| AST (IU/L) | 187 (84) | 184 (120.5) | 0.660 |
| ALT (IU/L) | 199.5 (83.25) | 195 (108.5) | 0.265 |
| Lactate (mmol/L) | 1.7 (0.2) | 1.25 (0.65) | |
| Ammonia (μmol/L) | 78 (16) | 54 (16) | |
| Total bilirubin (mg/dL) | 6.1 (3.92) | 2.3 (0.8) | |
| PT/INR | 1.8 (0.1) | 1.3 (0.2) | |
| * Median (IQR). ALF – acute liver failure; SET – supportive extracorporeal therapy; AST – aspartate transaminase; ALT – alanine tranaminase; PT – prothrombin time; INR – international normalized ratio; MAP – mean arterial pressure. | |||