27 June 2023 : Original article
A 15-Year Retrospective Study of Supportive Extracorporeal Therapies Including Plasma Exchange and Continuous Venovenous Hemodiafiltration of 114 Adults with Acute Liver Failure Awaiting Liver Transplantation
Ilhan Ocak
1ABCDEFG*
DOI: 10.12659/AOT.939745
Ann Transplant 2023; 28:e939745
Table 3 Laboratory values of all patients at admission and after treatment.
| Initial values* before SET | Last values* after SET | P values | |
|---|---|---|---|
| AST (IU/L) | 2317 (1426) | 184 (111.25) | <0.01 |
| ALT (IU/L) | 2357 (1331.75) | 197 (103.75) | <0.01 |
| Lactate (mmol/L) | 5.9 (1.47) | 1.5 (0.7) | <0.01 |
| Ammonia (μmol/L) | 132 (37) | 59 (24) | <0.01 |
| Total bilirubin (mg/dL) | 9.55 (8.75) | 2.75 (2.2) | <0.01 |
| PT/INR | 3.4 (0.72) | 1.35 (0.5) | <0.01 |
| pH | 7.3 (0.1) | 7.4 | <0.01 |
| MAP | 55 (6) | 67 (2) | <0.01 |
| Creatinine | 1.4 (0.5) | 0.6 (0.2) | <0.01 |
| Heart rate | 124 (21) | 91 (11) | <0.01 |
| PaO/FiO | 275 (35) | 302.5 (20.25) | <0.01 |
| * Median (IQR). SET – supportive extracorporeal therapy; AST – aspartate transaminase; ALT – alanine tranaminase; PT – prothrombin time; INR – international normalized ratio; MAP – mean arterial pressure. | |||