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21 November 2023: Original Paper

Predictors of Long-Term Outcomes After Liver Transplantation for Unresectable Metastatic Neuroendocrine Tumors

Mikołaj Kuncewicz 1BCDEF , Igor Piotr Jaszczyszyn 1BCDE , Kacper Karaban 1BCDE , Paweł Rykowski 1DEF* , Maciej Krasnodębski 1ADE , Marcin Morawski 1EF , Emilia Kruk 1B , Łukasz Koperski 2BC , Krzysztof Zieniewicz 1EF , Marek Krawczyk 1AEF , Michał Grąt 1AEF

DOI: 10.12659/AOT.941212

Ann Transplant 2023; 28:e941212

Table 3 Characteristics of the study group.

Number of missing data (%)Median or numberRange or %
Follow-up (months)0 (0%)72.50.3–235.1
Recipient Gender0 (0%)
 Female1157.89%
 Male842.11%
Recipient BMI4 (21.05%)24.917.2–31.0
Recipient age (y)0 (0%)5127–66
Donor age (y)1 (5.26%)4620–75
Time from primary lesion resection (months)4 (21.05%)19.51–82
Systemic treatment prior to LT0 (0%)1578.95%
Surgical treatment prior to LT0 (0%)947.37%
 LR333.33%
 RFA333.33%
 LR+RFA111.11%
 TACE222.22%
Caval anastomosis0 (0%)
 Piggy-back631.58%
 Classic1368.42%
Biliary anastomosis0 (0%)
 End-to-end1789.47%
 Roux-en-Y210.53%
PRBC transfusions (U)1 (5.26%)2.50–10
Primary tumor site0 (0%)
 Pancreas842.11%
 Small bowel631.58%
 Colon315.79%
 Stomach15.26%
 Unknown15.26%
Extrahepatic metastases in history (previously resected)0 (0%)736.84%
 Abdominal lymph nodes571.43%
 Abdominal lymph nodes+mediastinum114.29%
 Peritoneum114.29%
Extent of liver involvement (%)3 (15.79%)7.51–60
Number of tumors0 (0%)
 Numerous13
 Countable6
Number of countable tumors1 (5.26%)42–4
Size of tumor (mm)0 (0%)2–200
Ki67 index (%)0 (0%)22–16
Mitotic index0 (0%)10–10
MELD0 (0%)76–18
Cold ischemia (min)0 (0%)510240–720
BMI – body mass index; LT – liver transplantation; LR – liver resection; RFA – radiofrequency ablation; TACE – transarterial chemoembolization; PRBC – packed red blood cells; MELD – model for end-stage liver disease.

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Annals of Transplantation eISSN: 2329-0358
Annals of Transplantation eISSN: 2329-0358