28 November 2023>: Original Paper
Toll-Like Receptor 3 mRNA Expression of Peripheral Blood Mononuclear Cells Identifies Kidney Recipients with Potential for Improved Graft Performance
Sławomir C. Zmonarski 1ACDE* , Mirosław Banasik 1D , Marcelina Żabińska 1AB , Tomasz Gołębiowski 1BD , Joanna M. Zmonarska 2BF , Magdalena Krajewska 1FGDOI: 10.12659/AOT.941266
Ann Transplant 2023; 28:e941266
Table 5 Baseline vs follow-up assessment of the variability of related observations.
Descriptive data | Sign test | Wilcoxon test | |||||||
---|---|---|---|---|---|---|---|---|---|
Group | eGFR (ml/min) | Mean | Median | Q25–Q75 | Z | p= | Z | p= | |
Low-TLR3-mRNA | eGFR | Baseline | 45.7 | 46.0 | 33–59 | 0.25 | NS | 0.18 | NS |
Follow-up | 44.0 | 45.0 | 30–60 | ||||||
High-TLR3-mRNA | eGFR | Baseline | 50.0 | 47.0 | 38–61 | 2.52 | 0.012 | 1.97 | 0.048 |
Follow-up | 51.0 | 52.0 | 41–64 | ||||||
Low-TLR3-mRNA | eGFR >30 | Baseline | 52.9 | 52.5 | 42–61 | 0.58 | NS | 0.29 | NS |
Follow-up | 50.9 | 53.0 | 42–61 | ||||||
High-TLR3-mRNA | eGFR >30 | Baseline | 53.0 | 51.0 | 42–63 | 2.38 | 0.015 | 1.88 | 0.06 |
Follow-up | 54.0 | 54.5 | 43–66 | ||||||
Low-TLR3-mRNA | eGFR | Baseline | 31.5 | 33.0 | 25–40 | 0.35 | NS | 0.79 | NS |
Follow-up | 32.3 | 34.0 | 25–43 | ||||||
High-TLR3-mRNA | eGFR | Baseline | 34.8 | 37.0 | 32–41.5 | 2.40 | 0.016 | 2.45 | 0.014 |
Follow-up | 38.4 | 40.5 | 33–46 | ||||||
eGFR – estimated glomerular filtration rate (ml/min); Q25–Q75 – margins of lower and upper quartiles; Low-TLR3-mRNA – baseline expression of TLR3-mRNA below the median; High-TLR3-mRNA – baseline expression of TLR3-mRNA over median. |