05 December 2023: Database Analysis
Survival Outcomes After Double-Lung Transplantation for Refractory Lung-Limited Cancers and Incidence of Post-Transplant Lung Cancer
Jeeyeon Lee 12ABCDEF , Maria Jose Aguilera Chuchuca 1CDF , Jisang Yu 1BC , Liam Il-Young Chung 1AEF , Ankit Bharat 1ABCDEFG* , Young Kwang Chae 1A*DOI: 10.12659/AOT.941301
Ann Transplant 2023; 28:e941301
Table 2 Comparison of survivals in patients who received double-lung transplantation for lung cancer between case series and data from Organ Procurement Transplantation Network (OPTN).
| Variables | Case series (n=20) | OPTN data (n=15) | |
|---|---|---|---|
| Overall recurrence rate at reported point | 9/20 (45.0%) | 5/15 (33.3%) | |
| Overall survival rate at reported point | 10/20 (50.0%) | 3/15 (20.0%) | |
| Recurrence-free survival | Median (range, months) | 23.0 (2.0–76.0) | 11.2 (0.2–27.7) |
| 3-year | 16/20 (80.0%) | 10/15 (66.7%) | |
| 5-year | 11/20 (55.0%) | 10/15 (66.7%) | |
| Overall survival | Median (range, months) | 38.0 (2.0–144.0) | 15.9 (0.2–149.1) |
| 3-year | 14/20 (70.0%) | 4/15 (26.7%) | |
| 5-year | 611/20 (55.0%) | 3/15 (20.0%) | |
| Cancer-specific survival | Median (range, months) | 48.0 (2.0–144.0) | 27.7 (0.2–66.6) |
| 3-year | 14/18 (77.8%) | 3/7 (42.9%) | |
| 5-year | 11/18 (61.1%) | 3/7 (42.9%) | |