30 July 2024 : Original article
Comparative Study of Acute Kidney Injury in Liver Transplantation: Donation after Circulatory Death versus Brain Death
Benedikt Hilger1ABDEF*, Katja Frick1B, Rolf Erlebach1CD, Philipp Dutkowski2E, Rea Andermatt
1DEF, Sascha David1AE, Reto A. Schüpbach1E, Stephanie Klinzing1ADE
DOI: 10.12659/AOT.944077
Ann Transplant 2024; 29:e944077
Supplementary Table 1 Multivariable logistic regression model of KRT including significant interaction terms. All possible second-order intervariable interactions where tested and only significant interactions were included in the final model.
| Variable | log (OR) | 95% CI | p-value |
|---|---|---|---|
| DBD vs DCD | |||
| DBD | – | – | |
| DCD | 0.32 | −7.2, 8.1 | 0.933 |
| MELD Score | 0.09 | 0.03, 0.15 | 0.002 |
| eGFR baseline | −0.16 | −0.27, −0.05 | 0.005 |
| Recip. age (y) | 0.01 | −0.03, 0.06 | 0.619 |
| Recip. sex | |||
| Male | – | – | |
| Female | 0.01 | −0.97, 0.96 | 0.978 |
| Recip. BMI (kg/m) | 0.11 | 0.03, 0.20 | 0.007 |
| (eGFR baseline)^2 | 0.00 | 0.00, 0.00 | 0.008 |
| DBD vs DCD * MELD Score | |||
| DCD * MELD Score | −0.25 | −0.43, −0.09 | 0.003 |
| DBD vs DCD * eGFR baseline | |||
| DCD * eGFR baseline | 0.17 | 0.00, 0.35 | 0.053 |
| DBD vs DCD * (eGFR baseline)^2 | |||
| DCD * (eGFR baseline)^2 | 0.00 | 0.00, 0.00 | 0.020 |
| BMI – body mass index; CI – confidence interval; DBD – donation after brain death; DCD – donor after cardiac death; eGFR – estimated Glomerular Filtration Rate; KRT – renal replacement therapy; MELD – model for end-stage liver disease; OR – odds ratio. | |||