Prediction of Renal Graft Function 1 Year After Adult Deceased-Donor Kidney Transplantation Using Variables Available Prior to Transplantation

01 October 2024 : Original article

Ulrich Zwirner

^1ABCDEF*, Dennis Kleine-Döpke

^1ABCD, Alexander Wagner^1CDE, Simon Störzer^1BE, Felix Gronau^1EF, Oliver Beetz^2BDE, Nicolas Richter

^1BD, Wilfried Gwinner

^3DE, Ulf Kulik

^1ABE, Moritz Schmelzle^1DE, Harald Schrem

^4ABCDEF

DOI: 10.12659/AOT.944603

Ann Transplant 2024; 29:e944603

Introduction Material and Methods Results Discussion Conclusions References

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Table 6 Univariable linear regression analysis of transplantation-specific variables and their influence on eGFR 1 year after KTx.

Continuous data		R2	p-value
	Cold ischemia time (CIT) in min	<0.001	0.571
HLA mis-matches	Number of HLA-A mismatches	0.019	<0.001
	Number of HLA-B mismatches	0.024	<0.001
	Number of HLA-DR mismatches	0.012	<0.001
Results of the univariable linear regression analysis to determine significance of the influence of transplantation-specific variables on eGFR 1 year after KTx. All variables were additionally subjected to a principal component analysis for exclusion of multi-collinearity and were subsequently included into the multivariable linear regression modelling. CIT – cold ischemia time; HLA – human leukocyte antigen.

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